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Unilateral Cervical Polyneuropathies following Concurrent Bortezomib, Cetuximab, and Radiotherapy for Head and Neck Cancer
Joint Authors
Elghouche, Alhasan
Shokri, Tom
Qin, Yewen
Wargo, Susannah
Citrin, Deborah
Van Waes, Carter
Source
Case Reports in Otolaryngology
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We report a constellation of cervical polyneuropathies in a patient treated with concurrent bortezomib, cetuximab, and cisplatin alongside intensity modulated radiotherapy for carcinoma of the tonsil with neck metastasis.
The described deficits include brachial plexopathy, cervical sensory neuropathy, and oculosympathetic, recurrent laryngeal, and phrenic nerve palsies within the ipsilateral radiation field.
Radiation neuropathy involving the brachial plexus is typically associated with treatment of breast or lung cancer; however, increased awareness of this entity in the context of investigational agents with potential neuropathic effects in head and neck cancer has recently emerged.
With this report, we highlight radiation neuropathy in the setting of investigational therapy for head and neck cancer, particularly since these sequelae may present years after therapy and entail significant and often irreversible morbidity.
American Psychological Association (APA)
Elghouche, Alhasan& Shokri, Tom& Qin, Yewen& Wargo, Susannah& Citrin, Deborah& Van Waes, Carter. 2016. Unilateral Cervical Polyneuropathies following Concurrent Bortezomib, Cetuximab, and Radiotherapy for Head and Neck Cancer. Case Reports in Otolaryngology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1102266
Modern Language Association (MLA)
Elghouche, Alhasan…[et al.]. Unilateral Cervical Polyneuropathies following Concurrent Bortezomib, Cetuximab, and Radiotherapy for Head and Neck Cancer. Case Reports in Otolaryngology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1102266
American Medical Association (AMA)
Elghouche, Alhasan& Shokri, Tom& Qin, Yewen& Wargo, Susannah& Citrin, Deborah& Van Waes, Carter. Unilateral Cervical Polyneuropathies following Concurrent Bortezomib, Cetuximab, and Radiotherapy for Head and Neck Cancer. Case Reports in Otolaryngology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1102266
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102266