Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression
Joint Authors
Smith, Keely
Gomez-Rubio, Ana M.
Harris, Tomika S.
Brooks, Lauren E.
Mosquera, Ricardo A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-21
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We present a case of a 17-year-old Hispanic male with Arnold-Chiari Type 1 [AC-Type 1] with syringomyelia, status post decompression, who complains of exercise intolerance, headaches, and fatigue with exertion.
The patient was found to have diurnal hypercapnia and nocturnal alveolar hypoventilation.
Cardiopulmonary testing revealed blunting of the ventilatory response to the rise in carbon dioxide (CO2) resulting in failure of the parallel correlation between increased CO2 levels and ventilation; the expected vertical relationship between PETCO2 and minute ventilation during exercise was replaced with an almost horizontal relationship.
No new pathology of the brainstem was discovered by MRI or neurological evaluation to explain this phenomenon.
The patient was placed on continuous noninvasive open ventilation (NIOV) during the day and CPAP at night for a period of 6 months.
His pCO2 level decreased to normal limits and his symptoms improved; specifically, he experienced less headaches and fatigue during exercise.
In this report, we describe the abnormal response to exercise that patients with AC-Type 1 could potentially experience, even after decompression, characterized by the impairment of ventilator response to hypercapnia during exertion, reflecting a complete loss of chemical influence on breathing with no evidence of abnormality in the corticospinal pathway.
American Psychological Association (APA)
Smith, Keely& Gomez-Rubio, Ana M.& Harris, Tomika S.& Brooks, Lauren E.& Mosquera, Ricardo A.. 2016. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression. Case Reports in Pediatrics،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102448
Modern Language Association (MLA)
Smith, Keely…[et al.]. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression. Case Reports in Pediatrics No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1102448
American Medical Association (AMA)
Smith, Keely& Gomez-Rubio, Ana M.& Harris, Tomika S.& Brooks, Lauren E.& Mosquera, Ricardo A.. Unusual Ventilatory Response to Exercise in Patient with Arnold-Chiari Type 1 Malformation after Posterior Fossa Decompression. Case Reports in Pediatrics. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102448
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102448