Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment
Joint Authors
Kavuncuoğlu, Sultan
Aydoğmuş, Çiğdem
Tuğcu, Deniz
Dedeoglu, Reyhan
Bornaun, Helen
Öztarhan, Kazım
Çetinkaya, Merih
Erener-Ercan, Tugba
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-27
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Cardiac rhabdomyoma often shows spontaneous regression and usually requires only close follow-up.
However, patients with symptomatic inoperable rhabdomyomas may be candidates for everolimus treatment.
Our patient had multiple inoperable cardiac rhabdomyomas causing serious left ventricle outflow-tract obstruction that showed a dramatic reduction in the size after everolimus therapy, a mammalian target of rapamycin (mTOR) inhibitor.
After discontinuation of therapy, an increase in the diameter of masses occurred and everolimus was restarted.
After 6 months of treatment, rhabdomyomas decreased in size and therapy was stopped.
In conclusion, everolimus could be a possible novel therapy for neonates with clinically significant rhabdomyomas.
American Psychological Association (APA)
Bornaun, Helen& Öztarhan, Kazım& Erener-Ercan, Tugba& Dedeoglu, Reyhan& Tuğcu, Deniz& Aydoğmuş, Çiğdem…[et al.]. 2016. Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment. Case Reports in Pediatrics،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102456
Modern Language Association (MLA)
Bornaun, Helen…[et al.]. Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment. Case Reports in Pediatrics No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1102456
American Medical Association (AMA)
Bornaun, Helen& Öztarhan, Kazım& Erener-Ercan, Tugba& Dedeoglu, Reyhan& Tuğcu, Deniz& Aydoğmuş, Çiğdem…[et al.]. Regression of Cardiac Rhabdomyomas in a Neonate after Everolimus Treatment. Case Reports in Pediatrics. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102456
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102456