Hemorrhagic Pericardial Effusion with Tamponade: A Rare Adverse Effect of Infliximab—Case Report and Literature Review
Joint Authors
Lather, Henry D.
Kahlenberg, J. Michelle
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Introduction.
Antitumor necrosis factor (TNF) alpha agents are commonly used biologic therapies for a wide variety of rheumatic and inflammatory diseases.
Here, we present a case of hemorrhagic pericarditis as a consequence of infliximab and review the literature on pericardial complications stemming from this drug class.
Methods.
For the literature review, search terms using versions of antitumor necrosis factor alpha AND pericardial effusion OR pericarditis OR pleuropericarditis OR cardiac tamponade were used.
Results.
Pericarditis is a rare but serious complication of anti-TNF based therapy, and hemorrhagic fluid is even more rare, with only one additional case reported.
It is likely that this complication was secondary to a robust immune response to very high titer anti-infliximab antibodies.
Providers should be aware that this complication can occur and that abnormal elevations in procalcitonin may accompany this unusual finding.
American Psychological Association (APA)
Lather, Henry D.& Kahlenberg, J. Michelle. 2016. Hemorrhagic Pericardial Effusion with Tamponade: A Rare Adverse Effect of Infliximab—Case Report and Literature Review. Case Reports in Rheumatology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102635
Modern Language Association (MLA)
Lather, Henry D.& Kahlenberg, J. Michelle. Hemorrhagic Pericardial Effusion with Tamponade: A Rare Adverse Effect of Infliximab—Case Report and Literature Review. Case Reports in Rheumatology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1102635
American Medical Association (AMA)
Lather, Henry D.& Kahlenberg, J. Michelle. Hemorrhagic Pericardial Effusion with Tamponade: A Rare Adverse Effect of Infliximab—Case Report and Literature Review. Case Reports in Rheumatology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102635
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102635