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Toxic Epidermal Necrolysis-Like Lesions and Systemic Lupus Erythematosus Possibly Triggered by Sulfasalazine
Joint Authors
Krabbe, Simon
Gül, Cigdem
Andersen, Bjarne
Tvede, Niels
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
This case report describes a patient with arthritis of the large joints, bilateral sacroiliitis, and positive anti-SSA and anti-dsDNA antibody, who received sulfasalazine and shortly thereafter became critically ill.
He developed toxic epidermal necrolysis, hemolytic anemia, lymphopenia, markedly elevated ferritin, and muscle wasting.
A diagnosis of systemic lupus erythematosus was made, and mycophenolate mofetil and systemic glucocorticoids brought this severe disease under control.
Toxic epidermal necrolysis-like lesions and hemophagocytic syndrome have been reported as manifestations of systemic lupus erythematosus.
This patient possibly had spondyloarthritis or an undifferentiated connective tissue disease at presentation, and we suggest, based on the timing of events, that sulfasalazine may have acted as a trigger of the severe disease manifestations.
American Psychological Association (APA)
Krabbe, Simon& Gül, Cigdem& Andersen, Bjarne& Tvede, Niels. 2016. Toxic Epidermal Necrolysis-Like Lesions and Systemic Lupus Erythematosus Possibly Triggered by Sulfasalazine. Case Reports in Rheumatology،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102646
Modern Language Association (MLA)
Krabbe, Simon…[et al.]. Toxic Epidermal Necrolysis-Like Lesions and Systemic Lupus Erythematosus Possibly Triggered by Sulfasalazine. Case Reports in Rheumatology No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1102646
American Medical Association (AMA)
Krabbe, Simon& Gül, Cigdem& Andersen, Bjarne& Tvede, Niels. Toxic Epidermal Necrolysis-Like Lesions and Systemic Lupus Erythematosus Possibly Triggered by Sulfasalazine. Case Reports in Rheumatology. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102646
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102646