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A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma
Joint Authors
Lee, Cody M.
Girnita, Diana
Sharma, Arundhati
Khanna, Surabhi
Elwing, Jean M.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Systemic sclerosis is a rare autoimmune disorder with a wide spectrum of clinical manifestations and a multitude of autoantibodies that are associated with it.
In the past several years, advances in serologic testing have led to research indicating important prognostic and phenotypic associations with certain subsets of autoantibodies.
In particular, anti-RNA polymerase III (anti-RNAP III) has been associated with diffuse cutaneous disease, scleroderma renal crisis, a temporal relationship with malignancy, myositis, synovitis, joint contractures, and gastric antral vascular ectasia.
However, anti-RNAP III has not been associated with systemic sclerosis sine scleroderma.
We describe a patient with an atypical presentation of anti-RNAP III positive systemic sclerosis sine scleroderma who presented without the typical features of anti-RNAP III disease.
Instead, she presented with critical digital ischemia, pulmonary arterial hypertension, gastroesophageal reflux disease, interstitial lung disease, and no clinically detectable sclerodactyly.
American Psychological Association (APA)
Lee, Cody M.& Girnita, Diana& Sharma, Arundhati& Khanna, Surabhi& Elwing, Jean M.. 2016. A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma. Case Reports in Rheumatology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1102673
Modern Language Association (MLA)
Lee, Cody M.…[et al.]. A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma. Case Reports in Rheumatology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1102673
American Medical Association (AMA)
Lee, Cody M.& Girnita, Diana& Sharma, Arundhati& Khanna, Surabhi& Elwing, Jean M.. A Unique Presentation of Anti-RNA Polymerase III Positive Systemic Sclerosis Sine Scleroderma. Case Reports in Rheumatology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1102673
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102673