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Adenocarcinoma of the Right Colon in a Patient with Bloom Syndrome
Joint Authors
Rossi, Debora Helena
Ayrizono, Maria de Lourdes Setsuko
Leal, Raquel Franco
Coy, Cláudio Saddy Rodrigues
Martinez, Carlos Augusto Real
Pinheiro, Lilian Vital
Camargo, Michel Gardere
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Bloom syndrome (BS) is an inherited disorder due to mutation in BLM gene.
The diagnosis of BS should be considered in patients with growth retardation of prenatal onset, a photosensitive rash in a butterfly distribution over the cheeks, and an increased risk of cancer at an early age.
Clinical manifestations also include short stature, dolichocephaly, prominent ears, micrognathia, malar hypoplasia and a high-pitched voice, immunodeficiency, type II diabetes, and hypogonadism associated with male infertility and female subfertility.
The aim of this report is to describe case of patient with BS who developed adenocarcinoma of the cecum, successfully treated by right colectomy.
Case Report.
A 40-year-old man underwent colonoscopy to investigate the cause of his diarrhea, weight loss, and anemia.
The patient knew that he was a carrier of BS diagnosed at young age.
The colonoscopy showed an expansive and vegetating mass with 5.5 cm in diameter, located within the ascending colon.
Histopathological analysis of tissue fragments collected during colonoscopy confirmed the presence of tubular adenocarcinoma, and he was referred for an oncological right colectomy.
The procedure was performed without complications, and the patient was discharged on the fifth postoperative day.
Histopathological examination of the surgical specimen confirmed the presence of a grade II tubular adenocarcinoma (stage IIA).
The patient is currently well five years after surgery, without clinical or endoscopic signs of relapse in a multidisciplinary approach for the monitoring of comorbidities related to BS.
Conclusion.
Despite the development of colorectal cancer to be, a possibility rarely described the present case shows the need for early screening for colorectal cancer in all patients affected by BS.
American Psychological Association (APA)
Martinez, Carlos Augusto Real& Pinheiro, Lilian Vital& Rossi, Debora Helena& Camargo, Michel Gardere& Ayrizono, Maria de Lourdes Setsuko& Leal, Raquel Franco…[et al.]. 2016. Adenocarcinoma of the Right Colon in a Patient with Bloom Syndrome. Case Reports in Surgery،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1102732
Modern Language Association (MLA)
Martinez, Carlos Augusto Real…[et al.]. Adenocarcinoma of the Right Colon in a Patient with Bloom Syndrome. Case Reports in Surgery No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1102732
American Medical Association (AMA)
Martinez, Carlos Augusto Real& Pinheiro, Lilian Vital& Rossi, Debora Helena& Camargo, Michel Gardere& Ayrizono, Maria de Lourdes Setsuko& Leal, Raquel Franco…[et al.]. Adenocarcinoma of the Right Colon in a Patient with Bloom Syndrome. Case Reports in Surgery. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1102732
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102732