First Autologous Cord Blood Therapy for Pediatric Ischemic Stroke and Cerebral Palsy Caused by Cephalic Molding during Birth: Individual Treatment with Mononuclear Cells
Joint Authors
Source
Case Reports in Transplantation
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Intracranial laceration due to traumatic birth injury is an extremely rare event affecting approximately one newborn per a population of 4.5 million.
However, depending on the mode of injury, the resulting brain damage may lead to lifelong sequelae, for example, cerebral palsy for which there is no cure at present.
Here we report a rare case of neonatal arterial ischemic stroke and cerebral palsy caused by fetal traumatic molding and parietal depression of the head during delivery caused by functional cephalopelvic disproportion due to a “long pelvis.” This patient was treated by autologous cord blood mononuclear cells (45.8 mL, cryopreserved, TNC 2.53 × 10 e 8 ) with a remarkable recovery.
Active rehabilitation was provided weekly.
Follow-up examinations were at 3, 18, 34, and 57 months.
Generous use of neonatal head MRI in case of molding, craniofacial deformity, and a sentinel event during parturition is advocated to enhance diagnosis of neonatal brain damage as a basis for fast and potentially causative treatment modalities including autologous cord blood transplantation in a timely manner.
American Psychological Association (APA)
Jensen, A.& Hamelmann, E.. 2016. First Autologous Cord Blood Therapy for Pediatric Ischemic Stroke and Cerebral Palsy Caused by Cephalic Molding during Birth: Individual Treatment with Mononuclear Cells. Case Reports in Transplantation،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1102920
Modern Language Association (MLA)
Jensen, A.& Hamelmann, E.. First Autologous Cord Blood Therapy for Pediatric Ischemic Stroke and Cerebral Palsy Caused by Cephalic Molding during Birth: Individual Treatment with Mononuclear Cells. Case Reports in Transplantation No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1102920
American Medical Association (AMA)
Jensen, A.& Hamelmann, E.. First Autologous Cord Blood Therapy for Pediatric Ischemic Stroke and Cerebral Palsy Caused by Cephalic Molding during Birth: Individual Treatment with Mononuclear Cells. Case Reports in Transplantation. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1102920
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102920