Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis
Joint Authors
Moinuddin, Irfan
Bracamonte, Erika
Thajudeen, Bijin
Madhrira, Machaiah
Popovtzer, Mordecai
Sussman, Amy N.
Kadambi, Pradeep V.
Source
Case Reports in Transplantation
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-17
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Acute vascular rejection (AVR) is characterized by intimal arteritis in addition to tubulitis and interstitial inflammation.
It is associated with a poorer prognosis compared to tubulointerstitial rejection (AIR) and AVR is associated with a higher rate of graft loss than AIR.
The prognosis and treatment of arteritis without tubulitis and interstitial inflammation (isolated v1 lesion) are still controversial.
We report a case of a patient who had a biopsy of the kidney allograft for evaluation of slow graft function.
The biopsy revealed an isolated v1 lesion.
However, we chose not to augment immunosuppression.
The patient’s kidney allograft function improved over time with close monitoring.
Repeat biopsy a year later showed no evidence of endothelialitis and relatively unchanged fibrosis and no other abnormalities.
Although it is suggested that most cases of isolated v1 lesions will respond to corticosteroids or T cell depleting therapies, some cases will improve with conservative management.
Further studies are needed to determine which cases could be managed conservatively.
American Psychological Association (APA)
Moinuddin, Irfan& Thajudeen, Bijin& Sussman, Amy N.& Madhrira, Machaiah& Bracamonte, Erika& Popovtzer, Mordecai…[et al.]. 2016. Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis. Case Reports in Transplantation،Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102928
Modern Language Association (MLA)
Moinuddin, Irfan…[et al.]. Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis. Case Reports in Transplantation No. 2016 (2016), pp.1-3.
https://search.emarefa.net/detail/BIM-1102928
American Medical Association (AMA)
Moinuddin, Irfan& Thajudeen, Bijin& Sussman, Amy N.& Madhrira, Machaiah& Bracamonte, Erika& Popovtzer, Mordecai…[et al.]. Early Posttransplant Isolated v1 Lesion Does Not Need to Be Treated and Does Not Lead to Increased Fibrosis. Case Reports in Transplantation. 2016. Vol. 2016, no. 2016, pp.1-3.
https://search.emarefa.net/detail/BIM-1102928
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1102928