Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU
Joint Authors
Gökmen, Necati
Koca, Uğur
Ergan, Begüm
Ergün, Recai
Çalışkan, Taner
Aydın, Kutlay
Tokur, Murat Emre
Savran, Yusuf
Cömert, Bilgin
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
We sought to identify possible risk factors associated with mortality in patients with high-risk pulmonary embolism (PE) after intensive care unit (ICU) admission.
Patients and Methods.
PE patients, diagnosed with computer tomography pulmonary angiography, were included from two ICUs and were categorized into groups: group 1 high-risk patients and group 2 intermediate/low-risk patients.
Results.
Fifty-six patients were included.
Of them, 41 (73.2%) were group 1 and 15 (26.7%) were group 2.
When compared to group 2, need for vasopressor therapy (0 vs 68.3%; p<0.001) and need for invasive mechanical ventilation (6.7 vs 36.6%; p=0.043) were more frequent in group 1.
The treatment of choice for group 1 was thrombolytic therapy in 29 (70.7%) and anticoagulation in 12 (29.3%) patients.
ICU mortality for group 1 was 31.7% (n=13).
In multivariate logistic regression analysis, APACHE II score >18 (OR 42.47 95% CI 1.50–1201.1), invasive mechanical ventilation (OR 30.10 95% CI 1.96–463.31), and thrombolytic therapy (OR 0.03 95% CI 0.01–0.98) were found as independent predictors of mortality.
Conclusion.
In high-risk PE, admission APACHE II score and need for invasive mechanical ventilation may predict death in ICU.
Thrombolytic therapy seems to be beneficial in these patients.
American Psychological Association (APA)
Ergan, Begüm& Ergün, Recai& Çalışkan, Taner& Aydın, Kutlay& Tokur, Murat Emre& Savran, Yusuf…[et al.]. 2016. Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103171
Modern Language Association (MLA)
Ergan, Begüm…[et al.]. Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU. Canadian Respiratory Journal No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103171
American Medical Association (AMA)
Ergan, Begüm& Ergün, Recai& Çalışkan, Taner& Aydın, Kutlay& Tokur, Murat Emre& Savran, Yusuf…[et al.]. Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103171
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103171