Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography
Joint Authors
Fraser, John F.
Ramanathan, Kollengode
Mohammed, Hend
Hopkins, Peter
Corley, Amanda
Caruana, Lawrence
Dunster, Kimble R.
Barnett, Adrian
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Lung transplantation is the optimal treatment for end stage lung disease.
Donor shortage necessitates single-lung transplants (SLT), yet minimal data exists regarding regional ventilation in diseased versus transplanted lung measured by Electrical Impedance Tomography (EIT).
Method.
We aimed to determine regional ventilation in six SLT outpatients using EIT.
We assessed end expiratory volume and tidal volumes.
End expiratory lung impedance (EELI) and Global Tidal Variation of Impedance were assessed in supine, right lateral, left lateral, sitting, and standing positions in transplanted and diseased lungs.
A mixed model with random intercept per subject was used for statistical analysis.
Results.
EELI was significantly altered between diseased and transplanted lungs whilst lying on right and left side.
One patient demonstrated pendelluft between lungs and was therefore excluded for further comparison of tidal variation.
Tidal variation was significantly higher in the transplanted lung for the remaining five patients in all positions, except when lying on the right side.
Conclusion.
Ventilation to transplanted lung is better than diseased lung, especially in lateral positions.
Positioning in patients with active unilateral lung pathologies will be implicated.
This is the first study demonstrating changes in regional ventilation, associated with changes of position between transplanted and diseased lung.
American Psychological Association (APA)
Ramanathan, Kollengode& Mohammed, Hend& Hopkins, Peter& Corley, Amanda& Caruana, Lawrence& Dunster, Kimble R.…[et al.]. 2016. Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103173
Modern Language Association (MLA)
Ramanathan, Kollengode…[et al.]. Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography. Canadian Respiratory Journal No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103173
American Medical Association (AMA)
Ramanathan, Kollengode& Mohammed, Hend& Hopkins, Peter& Corley, Amanda& Caruana, Lawrence& Dunster, Kimble R.…[et al.]. Single-Lung Transplant Results in Position Dependent Changes in Regional Ventilation: An Observational Case Series Using Electrical Impedance Tomography. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103173
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103173