Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?
Joint Authors
Lemaitre, C.
Dominique, S.
Billoud, E.
Eliezer, M.
Montialoux, H.
Quillard, M.
Riachi, G.
Koning, E.
Morisse-Pradier, H.
Savoye, G.
Savoye-Collet, C.
Goria, O.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-26
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Cystic fibrosis-associated liver disease (CFLD) is a major cause of death.
The objective of our retrospective study was to describe the relevance of magnetic resonance imaging (MRI) and liver stiffness measurement (LSM) for CFLD evaluation.
Methods.
All cystic fibrosis adult patients evaluated by MRI and LSM were included.
MR signs of portal hypertension (PHT), dysmorphia, or cholangitis were collected and LSM expressed in kPa and Metavir.
Results.
Of 25 patients, 52% had abnormal MRI.
Median LSM was 5.7 kPa (3.4–9.9).
Three patients had F2 score and one had F3 score.
In patients with PHT, LSM was 7.85 kPa (3.7–9.9) compared to 5 (3.4–7.5) in others, p = 0.02 .
In patients with abnormal liver function tests, 50% had increased LSM (≥F2), whereas 94% with normal tests had normal LSM ( p = 0.04 ).
Seven patients had abnormal MRI despite normal ultrasonography.
Conclusions.
MRI and LSM provide useful information on CFLD and may help to screen patients with PHT.
American Psychological Association (APA)
Lemaitre, C.& Dominique, S.& Billoud, E.& Eliezer, M.& Montialoux, H.& Quillard, M.…[et al.]. 2016. Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103202
Modern Language Association (MLA)
Lemaitre, C.…[et al.]. Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?. Canadian Respiratory Journal No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103202
American Medical Association (AMA)
Lemaitre, C.& Dominique, S.& Billoud, E.& Eliezer, M.& Montialoux, H.& Quillard, M.…[et al.]. Relevance of 3D Cholangiography and Transient Elastography to Assess Cystic Fibrosis-Associated Liver Disease?. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103202
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103202