Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma
Joint Authors
Bentur, L.
Vilozni, Daphna
Hakim, Fahed
Livnat, Galit
Ofek, Miryam
Bar-Yoseph, Ronen
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A reversibility test by an increase of greater than 12% in FEV1 can support a diagnosis of asthma and alter a patient’s treatment plan but may not be applicable to the young ages.
We retrospectively gathered spirometric data from 85/271 asthmatic children having mild obstruction (FEV1 > 80% predicted), age 2.6–6.9 years.
Spirometry was performed before and 20 min after inhalation of 200 mcg Albuterol.
We defined a deviation below −1.64 z scores from control as obstruction and an increased above 1.64 scores from control as a positive response to bronchodilators.
Sensitivity of the index was considered significant if it captured >68% of the participants.
The sensitivity of detecting airway obstruction in these children by FEV1 was 15.3% and 62.4% by FEF25–75.
A positive response to Albuterol was an increase of 9.2% for FEV1 (12% for adults) and 18.5% for FEF25–75.
The sensitivity for detecting a response to Albuterol in mild asthma was 64.7% by FEV1 and 91.8% by FEF25–75.
Young children having normal spirometry can demonstrate airway reversibility.
The response of spirometry parameters to bronchodilators may be more sensitive than obstruction detection and may help to support the diagnosis of asthma and adjust treatment plan.
American Psychological Association (APA)
Vilozni, Daphna& Hakim, Fahed& Livnat, Galit& Ofek, Miryam& Bar-Yoseph, Ronen& Bentur, L.. 2016. Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103210
Modern Language Association (MLA)
Vilozni, Daphna…[et al.]. Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma. Canadian Respiratory Journal No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103210
American Medical Association (AMA)
Vilozni, Daphna& Hakim, Fahed& Livnat, Galit& Ofek, Miryam& Bar-Yoseph, Ronen& Bentur, L.. Assessment of Airway Bronchodilation by Spirometry Compared to Airway Obstruction in Young Children with Asthma. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103210
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103210