Respiratory Presentation of Pediatric Patients in the 2014 Enterovirus D68 Outbreak
Joint Authors
Martin, Georgina
Li, Rachel
Cook, Victoria E.
Carwana, Matthew
Tilley, Peter
Sauve, Laura
Tang, Patrick
Kapur, Akshat
Yang, Connie L.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
In the fall of 2014, a North American outbreak of enterovirus D68 resulted in a significant number of pediatric hospital admissions for respiratory illness throughout North America.
This study characterized the clinical presentation and risk factors for a severe clinical course in children admitted to British Columbia Children’s Hospital during the 2014 outbreak.
Methods.
Retrospective chart review of patients with confirmed EV-D68 infection admitted to BCCH with respiratory symptoms in the fall of 2014.
Past medical history, clinical presentation, management, and course in hospital was collected and analyzed using descriptive statistics.
Comparison was made between those that did and did not require ICU admission to identify risk factors.
Results.
Thirty-four patients were included (median age 7.5 years).
Fifty-three percent of children had a prior history of wheeze, 32% had other preexisting medical comorbidities, and 15% were previously healthy.
Ten children (29%) were admitted to the pediatric intensive care unit.
The presence of complex medical conditions (excluding wheezing) ( P = 0.03 ) and copathogens was associated with PICU admission ( P = 0.02 ).
Conclusions.
EV-D68 infection resulted in severe, prolonged presentations of asthma-like illness in the hospitalized pediatric population.
Patients with a prior history of wheeze and preexisting medical comorbidities appear to be most severely affected, but the virus can also cause wheezing in previously well children.
American Psychological Association (APA)
Martin, Georgina& Li, Rachel& Cook, Victoria E.& Carwana, Matthew& Tilley, Peter& Sauve, Laura…[et al.]. 2016. Respiratory Presentation of Pediatric Patients in the 2014 Enterovirus D68 Outbreak. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103250
Modern Language Association (MLA)
Martin, Georgina…[et al.]. Respiratory Presentation of Pediatric Patients in the 2014 Enterovirus D68 Outbreak. Canadian Respiratory Journal No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103250
American Medical Association (AMA)
Martin, Georgina& Li, Rachel& Cook, Victoria E.& Carwana, Matthew& Tilley, Peter& Sauve, Laura…[et al.]. Respiratory Presentation of Pediatric Patients in the 2014 Enterovirus D68 Outbreak. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103250
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103250