Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study
Joint Authors
Gangji, Azim S.
Rochwerg, Bram
Cheung, Jason H.
Ribic, Christine M.
Lalji, Faraz
Clarke, France J.
Gantareddy, Susheel
Ranganath, Nischal
Walele, Aziz
McDonald, Ellen
Meade, Maureen O.
Cook, Deborah J.
Wilkieson, Trevor T.
Clase, Catherine M.
Margetts, Peter J.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Bioimpedance analysis (BIA) is a novel method of assessing a patient’s volume status.
Objective.
We sought to determine the feasibility of using vector length (VL), derived from bioimpedance analysis (BIA), in the assessment of postresuscitation volume status in intensive care unit (ICU) patients with sepsis.
Method.
This was a prospective observational single-center study.
Our primary outcome was feasibility.
Secondary clinical outcomes included ventilator status and acute kidney injury.
Proof of concept was sought by correlating baseline VL measurements with other known measures of volume status.
Results.
BIA was feasible to perform in the ICU.
We screened 655 patients, identified 78 eligible patients, and approached 64 for consent.
We enrolled 60 patients (consent rate of 93.8%) over 12 months.
For each 50-unit increase in VL, there was an associated 22% increase in the probability of not requiring invasive mechanical ventilation (IMV) ( p = 0.13 ).
Baseline VL correlated with other measures of volume expansion including serum pro-BNP levels, peripheral edema, and central venous pressure (CVP).
Conclusion.
It is feasible to use BIA to predict postresuscitation volume status and patient-important outcomes in septic ICU patients.
Trial Registration.
This trial is registered with clinicaltrials.gov NCT01379404 registered on June 7, 2011.
American Psychological Association (APA)
Rochwerg, Bram& Cheung, Jason H.& Ribic, Christine M.& Lalji, Faraz& Clarke, France J.& Gantareddy, Susheel…[et al.]. 2016. Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103255
Modern Language Association (MLA)
Rochwerg, Bram…[et al.]. Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study. Canadian Respiratory Journal No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103255
American Medical Association (AMA)
Rochwerg, Bram& Cheung, Jason H.& Ribic, Christine M.& Lalji, Faraz& Clarke, France J.& Gantareddy, Susheel…[et al.]. Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103255
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103255