Predictors of Poor Outcomes in Critically Ill Adults with Hematologic Malignancy
Joint Authors
Cornish, Marion
Butler, Michael B.
Green, Robert S.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Patients with hematologic malignancy (HM) often require intensive care unit (ICU) admission due to organ failure through disease progression or treatment-related complications.
Objective.
To determine mortality and prognostic variables in adult patients with HM who were admitted to ICU.
Methods.
Structured chart review of all adult patients (age ≥ 18 years) with HM admitted to ICU of a Canadian tertiary care hospital between 2004 and 2014.
Outcome measures included mortality (ICU, 30-day, 60-day, and 12-month).
Logistic regression was performed to determine predictors of mortality.
Results.
Overall, there were 206 cases of HM admitted to the ICU during the study (mean age: 51.3 ± 13.6 years; 60% male).
Median stay was 3 days, with 14.1% requiring prolonged ICU admission.
ICU mortality was 45.6% and increased to 59.2% at 30 days, 62.6% at 60 days, and 74.3% at 12 months.
Predictors of increased ICU mortality included mechanical ventilation requirement and vasopressor therapy requirement, while admission to ICU postoperatively and having myeloma were associated with decreased mortality.
Conclusions.
Patients admitted to ICU with HM have high mortality (45.6%), which increased to 74.3% at 1 year.
Analysis of multiple variables identified critical illness, postsurgical admission, and myeloma as predictors of patient outcomes.
American Psychological Association (APA)
Cornish, Marion& Butler, Michael B.& Green, Robert S.. 2016. Predictors of Poor Outcomes in Critically Ill Adults with Hematologic Malignancy. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103262
Modern Language Association (MLA)
Cornish, Marion…[et al.]. Predictors of Poor Outcomes in Critically Ill Adults with Hematologic Malignancy. Canadian Respiratory Journal No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103262
American Medical Association (AMA)
Cornish, Marion& Butler, Michael B.& Green, Robert S.. Predictors of Poor Outcomes in Critically Ill Adults with Hematologic Malignancy. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103262
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103262