Hemodynamic Response to Upper Airway Obstruction in Hypertensive and Normotensive Pregnant Women
Joint Authors
Reid, John
Glew, Riley A.
Mink, Joe
Fenton, Mark
Skomro, Robert
Olatunbosun, Femi
Gjevre, John A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Mild obstructive sleep apnea is common in pregnancy and may have an exacerbating role in gestational hypertension, although currently the interaction between these two diseases is uncertain.
Methods.
We analyzed 43 pregnant subjects, 28 with gestational hypertension (GH) and 15 with normal healthy pregnancy, by level I polysomnography.
Additionally, diastolic and systolic blood pressure changes in response to obstructive respiratory events were measured by noninvasive beat-by-beat monitoring.
We also assessed a subgroup (n=27) of women with respiratory disturbance indexes <5, for blood pressure responses to very subtle obstructive respiratory disturbances (“airflow reductions”).
Results.
The mean ± standard deviation respiratory disturbance index of our 28 GH women and 15 healthy pregnant women was 10.1±9.9 mmHg and 3.0±3.8 mmHg, respectively.
Systolic and diastolic pressure responses to these events were 30.1±12.8 mmHg and 16.0±6.1 mmHg for GH women and 29.1±14.2 mmHg and 14.3±7.7 mmHg for healthy women.
For the 27 women in whom we assessed for airflow reduction events, the hemodynamic responses were 27.1±12.3 mmHg systolic and 14.4±6.7 mmHg diastolic.
Interpretation.
Upper airway obstructive events of any severity are associated with a substantial transient blood pressure response in both healthy pregnant and GH women.
Whether or not these events have a clinically significant impact on women with GH remains uncertain.
American Psychological Association (APA)
Reid, John& Glew, Riley A.& Mink, Joe& Gjevre, John A.& Fenton, Mark& Skomro, Robert…[et al.]. 2016. Hemodynamic Response to Upper Airway Obstruction in Hypertensive and Normotensive Pregnant Women. Canadian Respiratory Journal،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103269
Modern Language Association (MLA)
Reid, John…[et al.]. Hemodynamic Response to Upper Airway Obstruction in Hypertensive and Normotensive Pregnant Women. Canadian Respiratory Journal No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103269
American Medical Association (AMA)
Reid, John& Glew, Riley A.& Mink, Joe& Gjevre, John A.& Fenton, Mark& Skomro, Robert…[et al.]. Hemodynamic Response to Upper Airway Obstruction in Hypertensive and Normotensive Pregnant Women. Canadian Respiratory Journal. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103269
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103269