The Role of Adenosine in Pulmonary Vein Isolation: A Critical Review
Joint Authors
Dallaglio, Paolo D.
Betts, Timothy R.
Ginks, Matthew
Bashir, Yaver
Anguera, Ignasi
Rajappan, Kim
Source
Cardiology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-15
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
The cornerstone of atrial fibrillation (AF) ablation is pulmonary vein isolation (PVI), which can be achieved in more than 95% of patients at the end of the procedure.
However, AF recurrence rates remain high and are related to recovery of PV conduction.
Adenosine testing is used to unmask dormant pulmonary vein conduction (DC).
The aim of this study is to review the available literature addressing the role of adenosine testing and determine the impact of ablation at sites of PV reconnection on freedom from AF.
Adenosine infusion, by restoring the excitability threshold, unmasks reversible injury that could lead to recovery of PV conduction.
The studies included in this review suggest that adenosine is useful to unmask nontransmural lesions at risk of reconnection and that further ablation at sites of DC is associated with improvement in freedom from AF.
Nevertheless it has been demonstrated that adenosine is not able to predict all veins at risk of later reconnection, which means that veins without DC are not necessarily at low risk.
The role of the waiting period in the setting of adenosine testing has also been analyzed, suggesting that in the acute phase adenosine use should be accompanied by enough waiting time.
American Psychological Association (APA)
Dallaglio, Paolo D.& Betts, Timothy R.& Ginks, Matthew& Bashir, Yaver& Anguera, Ignasi& Rajappan, Kim. 2016. The Role of Adenosine in Pulmonary Vein Isolation: A Critical Review. Cardiology Research and Practice،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1103304
Modern Language Association (MLA)
Dallaglio, Paolo D.…[et al.]. The Role of Adenosine in Pulmonary Vein Isolation: A Critical Review. Cardiology Research and Practice No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1103304
American Medical Association (AMA)
Dallaglio, Paolo D.& Betts, Timothy R.& Ginks, Matthew& Bashir, Yaver& Anguera, Ignasi& Rajappan, Kim. The Role of Adenosine in Pulmonary Vein Isolation: A Critical Review. Cardiology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1103304
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103304