Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction
Joint Authors
Zykov, Mikhail V.
Kashtalap, Vasily V.
Karetnikova, Victoria
Osokina, Anastasia
Gruzdeva, Olga
Uchasova, Evgenya
Kalaeva, Victoria
Shafranskaya, Kristina
Hryachkova, Oksana
Barbarash, Olga
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study aimed to evaluate the association between serum galectin levels and renal dysfunction in relation to in-hospital prognosis and unfavorable prognosis 1 year after ST-elevated myocardial infarction (STEMI).
Patients were assigned to two groups according to the cystatin C-based estimate of GFR on day 12 after STEMI: (1) STEMI patients with normal renal function (GFR based on cystatin C levels = 60 mL/min/1.73 m2) and (2) those with renal dysfunction (RD) (GFR based on cystatin C levels <60 mL/min/1.73 m2).
A decrease in GFR estimated from the CKD-EPI equation on day 12 was more frequently found in patients with a reduced GFR based on cystatin C levels (41.9%) compared with those without RD (21.3%).
Galectin levels exceeded the cut-off value (17.8 ng/mL) in 50.6% of cases in the group with GFR <60 mL/min/1.73 m2 and in 32% of cases in the group with a normal GFR.
The presence of RD and elevated galectin levels >17.8 ng/mL on day 12 after MI are independent predictors of an adverse prognosis at 1 year in STEMI patients.
Elevated galectin levels are directly correlated with the presence of early postinfarction angina.
American Psychological Association (APA)
Karetnikova, Victoria& Osokina, Anastasia& Gruzdeva, Olga& Uchasova, Evgenya& Zykov, Mikhail V.& Kalaeva, Victoria…[et al.]. 2016. Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction. Disease Markers،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103658
Modern Language Association (MLA)
Karetnikova, Victoria…[et al.]. Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction. Disease Markers No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103658
American Medical Association (AMA)
Karetnikova, Victoria& Osokina, Anastasia& Gruzdeva, Olga& Uchasova, Evgenya& Zykov, Mikhail V.& Kalaeva, Victoria…[et al.]. Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103658
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103658