A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology
Joint Authors
Rose, Brandon J.
Kooyman, D. L.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Matrix metalloproteinases are a class of enzymes involved in the degradation of extracellular matrix molecules.
While these molecules are exceptionally effective mediators of physiological tissue remodeling, as occurs in wound healing and during embryonic development, pathological upregulation has been implicated in many disease processes.
As effectors and indicators of pathological states, matrix metalloproteinases are excellent candidates in the diagnosis and assessment of these diseases.
The purpose of this review is to discuss matrix metalloproteinases as they pertain to cartilage health, both under physiological circumstances and in the instances of osteoarthritis and rheumatoid arthritis, and to discuss their utility as biomarkers in instances of the latter.
American Psychological Association (APA)
Rose, Brandon J.& Kooyman, D. L.. 2016. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103716
Modern Language Association (MLA)
Rose, Brandon J.& Kooyman, D. L.. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103716
American Medical Association (AMA)
Rose, Brandon J.& Kooyman, D. L.. A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103716
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103716