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Anti-Mullerian Hormone: Above and Beyond Conventional Ovarian Reserve Markers
Joint Authors
Fatima, Syeda Sadia
Jamil, Zehra
Ahmed, Khalid
Malik, Rabia
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Management of ovarian dysfunctions requires accurate estimation of ovarian reserve (OR).
Therefore, reproductive hormones and antral follicle count (AFC) are assessed to indicate OR.
Serum anti-Mullerian hormone (AMH) is a unique biomarker that has a critical role in folliculogenesis as well as steroidogenesis within ovaries.
Secretion from preantral and early antral follicles renders AMH as the earliest marker to show OR decline.
In this review we discuss the dynamics of circulating AMH that remarkably vary with sex and age.
As it emerges as a marker of gonadal development and reproductive disorders, here we summarize the role of AMH in female reproductive physiology and provide evidence of higher accuracy in predicting ovarian response to stimulation.
Further, we attempt to compile potential clinical applications in children and adults.
We propose that AMH evaluation has a potential role in effectively monitoring chemotherapy and pelvic radiation induced ovarian toxicity.
Furthermore, AMH guided ovarian stimulation can lead to individualization of therapeutic strategies for infertility treatment.
However future research on AMH levels within follicular fluid may pave the way to establish it as a marker of “quality” besides “quantity” of the growing follicles.
American Psychological Association (APA)
Jamil, Zehra& Fatima, Syeda Sadia& Ahmed, Khalid& Malik, Rabia. 2016. Anti-Mullerian Hormone: Above and Beyond Conventional Ovarian Reserve Markers. Disease Markers،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103723
Modern Language Association (MLA)
Jamil, Zehra…[et al.]. Anti-Mullerian Hormone: Above and Beyond Conventional Ovarian Reserve Markers. Disease Markers No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1103723
American Medical Association (AMA)
Jamil, Zehra& Fatima, Syeda Sadia& Ahmed, Khalid& Malik, Rabia. Anti-Mullerian Hormone: Above and Beyond Conventional Ovarian Reserve Markers. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1103723
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103723