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Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications
Joint Authors
Paz-Ares, Luis
Molina-Pinelo, Sonia
Ferrer, Irene
Quintanal-Villalonga, A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-26
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Lung cancer is a heterogeneous disease responsible for the most cases of cancer-related deaths.
The majority of patients are clinically diagnosed at advanced stages, with a poor survival rate.
For this reason, the identification of oncodrivers and novel biomarkers is decisive for the future clinical management of this pathology.
The rise of high throughput technologies popularly referred to as “omics” has accelerated the discovery of new biomarkers and drivers for this pathology.
Within them, tyrosine kinase receptors (TKRs) have proven to be of importance as diagnostic, prognostic, and predictive tools and, due to their molecular nature, as therapeutic targets.
Along this review, the role of TKRs in the different lung cancer histologies, research on improvement of anti-TKR therapy, and the current approaches to manage anti-TKR resistance will be discussed.
American Psychological Association (APA)
Quintanal-Villalonga, A.& Paz-Ares, Luis& Ferrer, Irene& Molina-Pinelo, Sonia. 2016. Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications. Disease Markers،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1103811
Modern Language Association (MLA)
Quintanal-Villalonga, A.…[et al.]. Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications. Disease Markers No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1103811
American Medical Association (AMA)
Quintanal-Villalonga, A.& Paz-Ares, Luis& Ferrer, Irene& Molina-Pinelo, Sonia. Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1103811
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103811