The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis
Joint Authors
Liu, Lei
Yue, Song
Wu, Jingyang
Zhang, Jiahua
Chen, Lei
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
In order to clarify previous ambiguous research conclusions, a meta-analysis was made to investigate the relationship between betatrophin levels in blood and type 2 diabetes mellitus (T2DM).
Methods.
We have searched all the English and Chinese references regarding the relationship between betatrophin and diabetes in database both manually and online.
Strict criteria have been established to include and exclude articles, with Mean and Standard Deviation as statistics to evaluate strength of association.
We have chosen either fixed- or random effect model according to heterogeneity inspection results and used Begg’s test and Egger’s test to analyze publication bias.
Results.
A total of 11 studies were included in this meta-analysis.
Meta-analysis indicated a significant association between betatrophin and T2DM (Mean: 329.46; 95% confidence interval: 182.51 to 476.42, P < 0.0001 ).
However, in the subgroup analysis, there was no significant statistic between betatrophin concentration and T2DM within Caucasian population (Mean: 98.40; 95% confidence interval: −1585.08 to 1781.88, P = 0.91 ).
Conclusions.
Such relationship may suggest preference for association between betatrophin and T2DM in different population.
American Psychological Association (APA)
Yue, Song& Wu, Jingyang& Zhang, Jiahua& Liu, Lei& Chen, Lei. 2016. The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis. Disease Markers،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103821
Modern Language Association (MLA)
Yue, Song…[et al.]. The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis. Disease Markers No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1103821
American Medical Association (AMA)
Yue, Song& Wu, Jingyang& Zhang, Jiahua& Liu, Lei& Chen, Lei. The Relationship between Betatrophin Levels in Blood and T2DM: A Systematic Review and Meta-Analysis. Disease Markers. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1103821
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103821