Macular Amyloidosis and Epstein-Barr Virus
Joint Authors
Nahidi, Yalda
Tayyebi Meibodi, Naser
Nazeri, Narges
Meshkat, Z.
Source
Dermatology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background.
Amyloidosis is extracellular precipitation of eosinophilic hyaline material of self-origin with special staining features and fibrillar ultrastructure.
Macular amyloidosis is limited to the skin, and several factors have been proposed for its pathogenesis.
Detection of Epstein-Barr virus (EBV) DNA in this lesion suggests that this virus can play a role in pathogenesis of this disease.
Objective.
EBV DNA detection was done on 30 skin samples with a diagnosis of macular amyloidosis and 31 healthy skin samples in the margin of removed melanocytic nevi by using PCR.
Results.
In patients positive for beta-globin gene in PCR, BLLF1 gene of EBV virus was positive in 23 patients (8 patients in case and 15 patients in the control group).
There was no significant difference in presence of EBV DNA between macular amyloidosis (3.8%) and control (23.8%) groups (P=0.08).
Conclusion.
The findings of this study showed that EBV is not involved in pathogenesis of macular amyloidosis.
American Psychological Association (APA)
Nahidi, Yalda& Tayyebi Meibodi, Naser& Meshkat, Z.& Nazeri, Narges. 2016. Macular Amyloidosis and Epstein-Barr Virus. Dermatology Research and Practice،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1103841
Modern Language Association (MLA)
Nahidi, Yalda…[et al.]. Macular Amyloidosis and Epstein-Barr Virus. Dermatology Research and Practice No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1103841
American Medical Association (AMA)
Nahidi, Yalda& Tayyebi Meibodi, Naser& Meshkat, Z.& Nazeri, Narges. Macular Amyloidosis and Epstein-Barr Virus. Dermatology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1103841
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103841