Effect of Dendrobium officinale Extraction on Gastric Carcinogenesis in Rats
Joint Authors
Zhao, Yi
Liu, Yan
Lan, Xi-Ming
Xu, Guo-Liang
Sun, You-Zhi
Li, Fei
Liu, Hong-Ning
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Dendrobium officinale (Tie Pi Shi Hu in Chinese) has been widely used to treat different diseases in China.
Anticancer effect is one of the important effects of Dendrobium officinale.
However, the molecular mechanism of its anticancer effect remains unclear.
In the present study, gastric carcinogenesis in rats was used to evaluate the effect of Dendrobium officinale on cancer, and its pharmacological mechanism was explored.
Dendrobium officinale extracts (4.8 and 2.4 g/kg) were orally administered to the rats of the gastric carcinogenesis model.
Compared with the cancer model group, the high dose of Dendrobium officinale extracts significantly inhibited the rate of carcinogenesis.
Further analysis revealed that Dendrobium officinale extracts could regulate the DNA damage, oxidative stress, and cytokines related with carcinogenesis and induce cell apoptosis in order to prevent gastric cancer.
American Psychological Association (APA)
Zhao, Yi& Liu, Yan& Lan, Xi-Ming& Xu, Guo-Liang& Sun, You-Zhi& Li, Fei…[et al.]. 2016. Effect of Dendrobium officinale Extraction on Gastric Carcinogenesis in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103893
Modern Language Association (MLA)
Zhao, Yi…[et al.]. Effect of Dendrobium officinale Extraction on Gastric Carcinogenesis in Rats. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103893
American Medical Association (AMA)
Zhao, Yi& Liu, Yan& Lan, Xi-Ming& Xu, Guo-Liang& Sun, You-Zhi& Li, Fei…[et al.]. Effect of Dendrobium officinale Extraction on Gastric Carcinogenesis in Rats. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103893
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103893