Modulatory Effect of Eui-E-In-Tang on Serum Leptin Concentration in Obese Korean Female Adults: A Randomized Controlled Trial
Joint Authors
Park, Wansu
Song, Yun-Kyung
Lee, Ji-Young
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Obesity is associated with chronic inflammation and cytokines.
However, to date, the relationship between the serum levels of cytokines in obese individuals and taking herbal drugs remains largely unexplored.
Methods.
Serum cytokines were assessed by multiplex cytokine profiling assay.
Serum samples of obese female Korean adults (obese group; n = 20 ) as well as normal female Korean adults (normal group; n = 21 ) were collected at the start and end of study period.
Twenty obese female Korean adults were randomized to receive Eui-E-In-Tang (Eui-E-In-Tang group; n = 9 ) at a daily dose of 9 g or a matched placebo (placebo group; n = 11 ) for 12 weeks.
Results.
According to investigating serum cytokine levels at the start point of this study, the serum C-peptide, insulin, leptin, lipocalin-2, and adipsin levels in the obese group were found to be significantly higher than in the normal group.
And the investigation of serum cytokine levels at the end point of this study demonstrated that mean serum leptin of Eui-E-In-Tang group was found to be significantly reduced ( P = 0.037 ).
Conclusions.
This study provides preliminary evidence that Eui-E-In-Tang may exert immunomodulatory effect via altering the circulating concentration of leptin in Korean female adults.
American Psychological Association (APA)
Song, Yun-Kyung& Lee, Ji-Young& Park, Wansu. 2016. Modulatory Effect of Eui-E-In-Tang on Serum Leptin Concentration in Obese Korean Female Adults: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103938
Modern Language Association (MLA)
Song, Yun-Kyung…[et al.]. Modulatory Effect of Eui-E-In-Tang on Serum Leptin Concentration in Obese Korean Female Adults: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1103938
American Medical Association (AMA)
Song, Yun-Kyung& Lee, Ji-Young& Park, Wansu. Modulatory Effect of Eui-E-In-Tang on Serum Leptin Concentration in Obese Korean Female Adults: A Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1103938
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103938