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Intra-Articular Hyaluronic Acid Compared to Traditional Conservative Treatment in Dogs with Osteoarthritis Associated with Hip Dysplasia
Joint Authors
Cassu, Renata N.
Nicácio, Gabriel M.
Carapeba, Gabriel O. L.
Cavaleti, Poliana
Brinholi, Rejane B.
Giuffrida, Rogério
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-26
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The purpose of this study was to compare the efficacy of the intra-articular (IA) hyaluronic acid injection to traditional conservative treatment (TCT) in dogs with osteoarthritis (OA) induced by hip dysplasia.
Sixteen dogs were distributed into two groups: Hyal: IA injection of hyaluronic acid (5–10 mg), and Control: IA injection with saline solution (0.5–1.0 mL) in combination with a TCT using an oral nutraceutical (750–1000 mg every 12 h for 90 days) and carprofen (2.2 mg/kg every 12 h for 15 days).
All dogs were assessed by a veterinarian on five occasions and the owner completed an assessment form (HCPI and CPBI) at the same time.
The data were analyzed using unpaired t test, ANOVA, and Tukey’s test ( P < 0.05 ).
Compared with baseline, lower scores were observed in both groups over the 90 days in the veterinarian evaluation, HCPI, and CPBI ( P < 0.001 ).
The Hyal group exhibited lower scores from 15 to 90 and 60 to 90 days, in the CBPI and in the veterinarian evaluation, respectively, compared to the Control group.
Both treatments reduced the clinical signs associated with hip OA.
However, more significant results were achieved with intra-articular hyaluronic acid injection.
American Psychological Association (APA)
Carapeba, Gabriel O. L.& Cavaleti, Poliana& Nicácio, Gabriel M.& Brinholi, Rejane B.& Giuffrida, Rogério& Cassu, Renata N.. 2016. Intra-Articular Hyaluronic Acid Compared to Traditional Conservative Treatment in Dogs with Osteoarthritis Associated with Hip Dysplasia. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1103965
Modern Language Association (MLA)
Carapeba, Gabriel O. L.…[et al.]. Intra-Articular Hyaluronic Acid Compared to Traditional Conservative Treatment in Dogs with Osteoarthritis Associated with Hip Dysplasia. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1103965
American Medical Association (AMA)
Carapeba, Gabriel O. L.& Cavaleti, Poliana& Nicácio, Gabriel M.& Brinholi, Rejane B.& Giuffrida, Rogério& Cassu, Renata N.. Intra-Articular Hyaluronic Acid Compared to Traditional Conservative Treatment in Dogs with Osteoarthritis Associated with Hip Dysplasia. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1103965
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103965