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Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis
Joint Authors
Li, Shuzhen
Lin, Jianping
Chen, Shaoqing
Lu, Meili
Li, Yanan
Su, Youxin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-13
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Chinese medicinal herbs may be useful for the treatment of hyperuricemia, but there has been no systematic assessment of their efficacy and safety.
Objectives.
To systematically assess the efficacy and safety of Chinese medicinal herbs for the treatment of hyperuricemia.
Methods.
Six electronic databases were searched from their inception to December 2015.
Randomized controlled clinical trials (RCTs) were included.
Cochrane criteria were applied to assess the risk of bias.
Data analysis was performed using RevMan software version 5.2.
Results.
Eleven RCTs with 838 patients were included.
There was no significant difference in serum uric acid between Chinese medicinal herbs and traditional Western medicine (SME: 0.19, 95% CI: −0.04 to 0.43; p=0.10).
In terms of overall efficacy, the Chinese medicinal herbs were significantly superior to Western medicine (RR: 1.11; 95% CI: 1.04 to 1.17; p=0.0007).
The Chinese medicinal herbs were better than Western medicine in reducing the adverse reactions (RR: 0.30; 95% CI: 0.15 to 0.62; p=0.001).
And all these funnel plots showed unlikelihood of publishing bias.
Conclusions.
The results indicate that Chinese medicinal herbs may have greater overall efficacy with fewer adverse drug reactions, although the evidence is weak owing to the low methodological quality and the small number of the included trials.
American Psychological Association (APA)
Lin, Jianping& Chen, Shaoqing& Li, Shuzhen& Lu, Meili& Li, Yanan& Su, Youxin. 2016. Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1103977
Modern Language Association (MLA)
Lin, Jianping…[et al.]. Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1103977
American Medical Association (AMA)
Lin, Jianping& Chen, Shaoqing& Li, Shuzhen& Lu, Meili& Li, Yanan& Su, Youxin. Efficacy and Safety of Chinese Medicinal Herbs for the Treatment of Hyperuricemia: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1103977
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103977