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Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1
Joint Authors
Li, Kefeng
Su, Jia-Hang
Diao, Rui-Gang
Lv, Shu-Guang
Mou, Xiao-Dong
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-18
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Woad root has been used for the prevention of influenza for hundreds of years in many Asian countries.
In this study, the antiviral modes of clemastanin B (CB), epigoitrin, phenylpropanoid portion (PEP), and the mixture of phenylpropanoids, alkaloids, and organic acid portions (PEP + ALK + OA) from wood root extract against influenza virus A FM1 were investigated.
The results revealed that CB, epigoitrin, PEP, and PEP + ALK + OA exert their anti-influenza activity via inhibiting the virus multiplication, prophylaxis, and blocking the virus attachment.
The primary mode of action of PEP and PEP + ALK + OA is the inhibition of virus replication.
The inhibitory effect on virus attachment and multiplication is the main modes for epigoitrin.
All the compounds or chemical portions from woad root extract tested in this study do not have direct virucidal activity.
Our results provided the comprehensive analysis of the antiviral mechanism of wood root extract.
American Psychological Association (APA)
Su, Jia-Hang& Diao, Rui-Gang& Lv, Shu-Guang& Mou, Xiao-Dong& Li, Kefeng. 2016. Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103989
Modern Language Association (MLA)
Su, Jia-Hang…[et al.]. Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103989
American Medical Association (AMA)
Su, Jia-Hang& Diao, Rui-Gang& Lv, Shu-Guang& Mou, Xiao-Dong& Li, Kefeng. Modes of Antiviral Action of Chemical Portions and Constituents from Woad Root Extract against Influenza Virus A FM1. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103989
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103989