Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect—Results of an Observational Study
Joint Authors
Scheffer, Christian
Debus, Marion
Heckmann, Christian
Girke, Matthias
Cysarz, Dirk
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Goitre with euthyroid function or with subclinical or mild hyperthyroidism due to thyroid autonomy is common.
In anthroposophic medicine various thyroid disorders are treated with Colchicum autumnale (CAU).
We examined the effects of CAU in patients with goitre of both functional states.
Patients and methods.
In an observational study, 24 patients with goitre having suppressed thyroid stimulating hormone (TSH) levels with normal or slightly elevated free thyroxine (fT4) and free triiodothyronine (fT3) (group 1, n=12) or normal TSH, fT3, and fT4 (group 2, n=12) were included.
After 3 months and after 6 to 12 months of CAU treatment, we investigated clinical pathology using the Hyperthyroid Symptom Scale (HSS), hormone status (TSH, fT4, and fT3), and thyroidal volume (tV).
Results.
After treatment with CAU, in group 1 the median HSS decreased from 4.5 (2.3–11.8) to 2 (1.3–3) (p<0.01) and fT3 decreased from 3.85 (3.5–4.78) to 3.45 (3.3–3.78) pg/mL (p<0.05).
In group 2 tV (13.9% (18.5%–6.1%)) and TSH (p<0.01) were reduced.
Linear regression for TSH and fT3 in both groups indicated a regulative therapeutic effect of CAU.
Conclusions.
CAU positively changed the clinical pathology of subclinical hyperthyroidism and thyroidal volume in patients with euthyroid goitre by normalization of the regulation of thyroidal hormones.
American Psychological Association (APA)
Scheffer, Christian& Debus, Marion& Heckmann, Christian& Cysarz, Dirk& Girke, Matthias. 2016. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect—Results of an Observational Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103991
Modern Language Association (MLA)
Scheffer, Christian…[et al.]. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect—Results of an Observational Study. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1103991
American Medical Association (AMA)
Scheffer, Christian& Debus, Marion& Heckmann, Christian& Cysarz, Dirk& Girke, Matthias. Colchicum autumnale in Patients with Goitre with Euthyroidism or Mild Hyperthyroidism: Indications for a Therapeutic Regulative Effect—Results of an Observational Study. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1103991
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1103991