![](/images/graphics-bg.png)
Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke
Joint Authors
Farhana, Kun Marisa
Malueka, Rusdy Ghazali
Wibowo, Samekto
Gofir, Abdul
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study aimed to determine the effectiveness of gotu kola (Centella asiatica) in improving cognitive function in patients with vascular cognitive impairment (VCI).
This study uses a quasi-experimental design.
Subjects in this study were patients with poststroke cognitive impairment who were treated at two hospitals in Yogyakarta, Indonesia.
The number of subjects was 48: 17 subjects were treated with 1000 mg/day of gotu kola extract, 17 subjects treated with 750 mg/day of gotu kola extract, and 14 subjects treated with 3 mg/day of folic acid for 6 weeks.
A Montreal Cognitive Assessment-Indonesian version (MoCA-Ina) was conducted at the beginning of treatment and after 6 weeks of therapy.
It was found that all trials effectively improved poststroke VCI based on MoCA-Ina scores over the course of the study.
There is no significant difference in ΔMoCA-Ina (score at the 6th week of treatment − score at the beginning) mean score among the three groups, indicating that gotu kola is as effective as folic acid in improving poststroke VCI.
Gotu kola was shown to be more effective than folic acid in improving memory domain.
This study suggested that gotu kola extract is effective in improving cognitive function after stroke.
American Psychological Association (APA)
Farhana, Kun Marisa& Malueka, Rusdy Ghazali& Wibowo, Samekto& Gofir, Abdul. 2016. Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104018
Modern Language Association (MLA)
Farhana, Kun Marisa…[et al.]. Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1104018
American Medical Association (AMA)
Farhana, Kun Marisa& Malueka, Rusdy Ghazali& Wibowo, Samekto& Gofir, Abdul. Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104018
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104018