Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools
Joint Authors
Lee, Guem-San
Doh, Eui-Jeong
Kim, Jung Hoon
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Atractylodes rhizomes have been used as the herbal medicine “Changchul” or “Baekchul,” according to their clinical purpose, in Korea, China, and Japan.
Among the Atractylodes species, the medicinal use of Atractylodes japonica has been controversial, as it is categorized as both Changchul and Baekchul in those countries, and, moreover, parts of the rhizome have been differently used, depending on age of the plant, in Korea.
Chromatographic fingerprinting by using HPLC combined with chemometric analyses and internal transcribed spacer (ITS) sequencing analysis were conducted to classify and identify 34 crude drugs derived from Atractylodes rhizomes.
The identification of the samples, authenticated by their morphological features as A.
japonica Koidz.
(Changchul and Baekchul), A.
chinensis Koidz., and A.
macrocephala Koidz., was confirmed as A.
japonica, A.
chinensis, and A.
macrocephala by ITS sequencing.
The results from chemometric analyses showed that the chemical components of the crude drugs from A.
japonica were significantly different from those from A.
macrocephala but were similar to those from A.
chinensis.
The analyses also suggested that the categorization by age of A.
japonica as Changchul or Baekchul is not recommended.
The results indicate that A.
japonica should be categorized as “Changchul” and should not be further categorized by age.
American Psychological Association (APA)
Kim, Jung Hoon& Doh, Eui-Jeong& Lee, Guem-San. 2016. Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104029
Modern Language Association (MLA)
Kim, Jung Hoon…[et al.]. Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1104029
American Medical Association (AMA)
Kim, Jung Hoon& Doh, Eui-Jeong& Lee, Guem-San. Evaluation of Medicinal Categorization of Atractylodes japonica Koidz. by Using Internal Transcribed Spacer Sequencing Analysis and HPLC Fingerprinting Combined with Statistical Tools. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104029
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104029