Analgesic Neural Circuits Are Activated by Electroacupuncture at Two Sets of Acupoints
Joint Authors
Hu, Man-Li
Hu, Kuang
Ding, Ming-Xing
Qiu, Zheng-Ying
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
To investigate analgesic neural circuits activated by electroacupuncture (EA) at different sets of acupoints in the brain, goats were stimulated by EA at set of Baihui-Santai acupoints or set of Housanli acupoints for 30 min.
The pain threshold was measured using the potassium iontophoresis method.
The levels of c-Fos were determined with Streptavidin-Biotin Complex immunohistochemistry.
The results showed pain threshold induced by EA at set of Baihui-Santai acupoints was 44.74 % ± 4.56 % higher than that by EA at set of Housanli acupoints ( 32.64 % ± 5.04 % ).
Compared with blank control, EA at two sets of acupoints increased c-Fos expression in the medial septal nucleus (MSN), the arcuate nucleus (ARC), the nucleus amygdala basalis (AB), the lateral habenula nucleus (HL), the ventrolateral periaqueductal grey (vlPAG), the locus coeruleus (LC), the nucleus raphe magnus (NRM), the pituitary gland, and spinal cord dorsal horn (SDH).
Compared with EA at set of Housanli points, EA at set of Baihui-Santai points induced increased c-Fos expression in AB but decrease in MSN, the paraventricular nucleus of the hypothalamus, HL, and SDH.
It suggests that ARC-PAG-NRM/LC-SDH and the hypothalamus-pituitary may be the common activated neural pathways taking part in EA-induced analgesia at the two sets of acupoints.
American Psychological Association (APA)
Hu, Man-Li& Qiu, Zheng-Ying& Hu, Kuang& Ding, Ming-Xing. 2016. Analgesic Neural Circuits Are Activated by Electroacupuncture at Two Sets of Acupoints. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104106
Modern Language Association (MLA)
Hu, Man-Li…[et al.]. Analgesic Neural Circuits Are Activated by Electroacupuncture at Two Sets of Acupoints. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1104106
American Medical Association (AMA)
Hu, Man-Li& Qiu, Zheng-Ying& Hu, Kuang& Ding, Ming-Xing. Analgesic Neural Circuits Are Activated by Electroacupuncture at Two Sets of Acupoints. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1104106
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104106