Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice
Joint Authors
Yu, Zhi
Yuan, Mengqian
Li, Yuqin
Wang, Yidan
Zhang, Na
Hu, XuanMing
Yin, Yin
Xu, Bin
Zhu, Bing
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The roles of the sympathetic and parasympathetic systems in mediating the effect of electroacupuncture (EA) at ST37 on jejunal motility have yet to be demonstrated.
Aim.
We used rats and mice to investigate the effect and mechanism of action of EA at ST37 on jejunal motility.
Methods.
Jejunal motility was recorded by a balloon placed in the jejunum and connected to a biological signal collection system through a transducer.
The effects of EA (3 mA) at ST37 were evaluated in Sprague-Dawley rats without drugs and with the administration of clenbuterol, propranolol, acetylcholine, and atropine.
Further, the efficacy of EA at different intensities (1/2/4/6/8 mA) was measured in wild-type mice and β1β2-/- mice and M2M3-/- mice.
Results.
In Sprague-Dawley rats, the excitatory effect of EA at ST37 on jejunal motility disappeared in the presence of the muscarinic receptor antagonist atropine.
EA at ST37 was less effective in M2M3-/- mice than in wild-type mice.
Furthermore, to a certain extent, there existed “intensity-response” relationship between jejunal motility and EA.
Conclusions.
EA at ST37 can enhance jejunal motility in rats and mice mainly via excitation of the parasympathetic pathway.
There is an “intensity-response” relationship between EA and effect on jejunal motility.
American Psychological Association (APA)
Yuan, Mengqian& Li, Yuqin& Wang, Yidan& Zhang, Na& Hu, XuanMing& Yin, Yin…[et al.]. 2016. Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104107
Modern Language Association (MLA)
Yuan, Mengqian…[et al.]. Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104107
American Medical Association (AMA)
Yuan, Mengqian& Li, Yuqin& Wang, Yidan& Zhang, Na& Hu, XuanMing& Yin, Yin…[et al.]. Electroacupuncture at ST37 Enhances Jejunal Motility via Excitation of the Parasympathetic System in Rats and Mice. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104107