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Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil
Joint Authors
Fernandes, Patricia Dias
Boylan, Fabio
Donald, Graciela Rocha
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Zanthoxylum piperitum DC.
(ZP) is a traditional medicinal plant used mainly in countries from Asia such as Japan.
This study aimed to investigate the antinociceptive effect of ZP essential oil (ZPEO).
The major component present in the essential oil was beta-phellandrene (29.39%).
Its antinociceptive activity was tested through animal models (formalin-, capsaicin-, and glutamate-induced paw licking and hot plate).
The anti-inflammatory effect was evaluated through the carrageenan-induced leukocyte migration into the subcutaneous air pouch (SAP), with measurement of cytokines.
The results showed antinociceptive effect for ZPEO for the first phase of the formalin-induced licking, glutamate, and hot plate tests.
However, ZPEO had no effect on reducing paw licking induced by capsaicin.
Finally, ZPEO had no effect against inflammation induced by carrageenan.
American Psychological Association (APA)
Donald, Graciela Rocha& Fernandes, Patricia Dias& Boylan, Fabio. 2016. Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104108
Modern Language Association (MLA)
Donald, Graciela Rocha…[et al.]. Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104108
American Medical Association (AMA)
Donald, Graciela Rocha& Fernandes, Patricia Dias& Boylan, Fabio. Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104108
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104108