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Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves
Joint Authors
Cardoso, Claudia Andrea Lima
Rocha, Paola dos Santos da
de Picoli Souza, Kely
Antunes, Kátia Avila
Baldivia, Débora da Silva
Casagrande, Junior Cesar
Argandoña, Eliana Janet Sanjinez
Vieira, Maria do Carmo
dos Santos, Edson Lucas
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Obesity is a worldwide epidemic that reduces life expectancy; therefore, the search for new alternative and effective treatments is ongoing.
The aim of the present investigation was to identify the chemical compounds in the hydroethanolic extract of leaves of Jacaranda decurrens subsp.
symmetrifoliolata and to evaluate their toxicity and antiobesity effects.
High-performance liquid chromatography was used to identify the chemical constituents, and acute toxicity was evaluated in rats treated with doses of 2 and 5 g·kg−1 body mass.
The antiobesity effect was determined in rats with hypercaloric diet-induced obesity.
Our results revealed the presence of compounds, such as jacaric, ursolic, and oleic acids, as well as luteolin, quercetin, and kaempferol, in the extract.
The acute toxicity tests revealed that rats treated with elevated doses of the extract showed no signs of toxicity.
The extract induced reduction in total body mass and the white adipose tissue depots.
The obese rats treated with the extract showed an increased fluid intake and feces excretion while their serum total cholesterol and triglyceride levels decreased compared to those in the controls, without any hematological changes.
Taken together, the results showed that the constituents of J.
decurrens extracts included phenolic compounds and exhibited antiobesity effects with no toxicity.
American Psychological Association (APA)
Antunes, Kátia Avila& Baldivia, Débora da Silva& Rocha, Paola dos Santos da& Casagrande, Junior Cesar& Argandoña, Eliana Janet Sanjinez& Vieira, Maria do Carmo…[et al.]. 2016. Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104143
Modern Language Association (MLA)
Antunes, Kátia Avila…[et al.]. Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104143
American Medical Association (AMA)
Antunes, Kátia Avila& Baldivia, Débora da Silva& Rocha, Paola dos Santos da& Casagrande, Junior Cesar& Argandoña, Eliana Janet Sanjinez& Vieira, Maria do Carmo…[et al.]. Antiobesity Effects of Hydroethanolic Extract of Jacaranda decurrens Leaves. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104143
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104143