Estimation of Bioactive Compound, Maslinic Acid by HPTLC, and Evaluation of Hepatoprotective Activity on Fruit Pulp of Ziziphus jujuba Mill. Cultivars in India
Joint Authors
Rajopadhye, Anagha
Upadhye, Anuradha S.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Fruits of Ziziphus jujuba Mill.
(family: Rhamnaceae), known as Indian jujube or “Ber,” are of potential nutritional and medicinal value.
The objectives of the present study were to estimate bioactive compound maslinic acid by HPTLC method and to evaluate in vitro antioxidant and hepatoprotective activity of eight cultivars of Indian jujube.
Maslinic acid and the fruit pulp of various cultivars of Indian jujube, namely, Gola, Sannur, Umaran, Mehrun, and Chhuhara, exhibited significantly high antioxidant and hepatoprotective activity.
HPTLC-densitometric method was developed for quantification of maslinic acid from fruits of Indian jujube cultivars.
The trend of occurrence of maslinic acid in fruits pulp extracts was as follows: Gola > Sannur > Umaran > Mehrun > Chhuhara > Wild > Kadaka > Apple.
A significant correlation was shown by maslinic acid content and prevention of oxidative stress induced by CCl4 in liver slice culture cell treated with extract.
Maslinic acid along with its other phytoconstituents like phenols, flavonoids, and ascorbic acid may act as a possible therapeutic agent for preventing hepatotoxicity caused by oxidative stress generated due to the prooxidants like CCl4.
This is the first report of fruit pulp extracts of Z.
jujube cultivars in India and maslinic acid preventing CCl4 induced damage in liver slice culture cell of mice.
American Psychological Association (APA)
Rajopadhye, Anagha& Upadhye, Anuradha S.. 2016. Estimation of Bioactive Compound, Maslinic Acid by HPTLC, and Evaluation of Hepatoprotective Activity on Fruit Pulp of Ziziphus jujuba Mill. Cultivars in India. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104171
Modern Language Association (MLA)
Rajopadhye, Anagha& Upadhye, Anuradha S.. Estimation of Bioactive Compound, Maslinic Acid by HPTLC, and Evaluation of Hepatoprotective Activity on Fruit Pulp of Ziziphus jujuba Mill. Cultivars in India. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104171
American Medical Association (AMA)
Rajopadhye, Anagha& Upadhye, Anuradha S.. Estimation of Bioactive Compound, Maslinic Acid by HPTLC, and Evaluation of Hepatoprotective Activity on Fruit Pulp of Ziziphus jujuba Mill. Cultivars in India. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104171
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104171