The Efficacy and Safety of Chinese Herbal Decoction in Type 2 Diabetes: A 5-Year Retrospective Study
Joint Authors
Yu, Xiaotong
Tong, Xiaolin
Zhao, Tian-Yu
Lian, Fengmei
Cui, Yashan
Cao, Yang
Tian, Jiaxing
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-30
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
The study was designed to assess the efficacy and safety of Chinese herbal decoction in treating outpatients with T2DM.
Methods.
All patients enrolled received decoction for at least 6 months.
The primary outcome was the control rate of HbA1c and the change in HbA1c.
FPG, 2hPG, HOMA-IR, and HOMA-β were also collected and evaluated.
Results.
The control rates after treatment at months 6, 12, 18, 24, 36, 48, and 60 were 45.07 % , 52.78 % , 47.22 % , 45.83 % , 50.00 % , 57.14 % , and 40.00 % .
Multiple linear regression showed the change of HbA1c has a significant relationship with the baseline HbA1c and duration of DM and BMI ( p < 0.05 ).
Both FPG and 2hPG levels significantly decreased compared to the baseline ( p < 0.05 ).
Chinese herbal decoction also improved islet cell function with decreased HOMA-IR and increased HOMA-β ( p < 0.05 ).
19 and 4 subjects deactivated the antidiabetes drugs or insulin, respectively, after taking decoction.
One subject developed DKD and one developed DPN, and another subject showed abnormal liver function which was irrelevant to decoction treatment.
Conclusions.
Chinese herbal decoction significantly enhanced the hypoglycemic action and had certain effect on protecting islet cell function.
As a candidate diabetes therapy, it may reduce the use of antidiabetes drugs and slow the progression to diabetes complications.
American Psychological Association (APA)
Tian, Jiaxing& Lian, Fengmei& Yu, Xiaotong& Cui, Yashan& Zhao, Tian-Yu& Cao, Yang…[et al.]. 2016. The Efficacy and Safety of Chinese Herbal Decoction in Type 2 Diabetes: A 5-Year Retrospective Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104213
Modern Language Association (MLA)
Tian, Jiaxing…[et al.]. The Efficacy and Safety of Chinese Herbal Decoction in Type 2 Diabetes: A 5-Year Retrospective Study. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1104213
American Medical Association (AMA)
Tian, Jiaxing& Lian, Fengmei& Yu, Xiaotong& Cui, Yashan& Zhao, Tian-Yu& Cao, Yang…[et al.]. The Efficacy and Safety of Chinese Herbal Decoction in Type 2 Diabetes: A 5-Year Retrospective Study. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1104213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104213