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Effects and Safety of Aqueous Extract of Poncirus fructus in Spinal Cord Injury with Neurogenic Bowel
Joint Authors
Kim, Ji Hee
Lee, Su Kyung
Joo, Min Cheol
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate the effects and safety of the aqueous extract of the dried, immature fruit of Poncirus trifoliata (L.) Raf., known as Poncirus fructus (PF), in spinal cord injury (SCI) patients with neurogenic bowel.
Methods.
Thirty-one SCI patients with neurogenic bowel were recruited.
Patients were evaluated based on clinical information, constipation score, Bristol Stool Form Scale, stool retention score using plain abdominal radiograph, and colon transit time.
PF was administered in dosages of 800 mg each prior to breakfast and lunch for 14 days.
Results.
The morphological feature of the stool before and after administration indicated a statistically significant difference from 3.52 ± 1.33 to 4.32 ± 1.44 points ( p < 0.05 ).
Stool retention score before and after administration of PF was represented with low significance (7.25 ± 1.60 to 6.46 ± 1.53 points) in the whole colon ( p < 0.05 ), and the colon transit time was significantly shortened (57.41 ± 20.7 to 41.2 ± 25.5 hours) in terms of the whole transit time ( p < 0.05 ).
Side effects were observed in 7 people (28.0%) consisting of 2 people with soft stools and 5 people with diarrhea.
Conclusion.
For SCI patients, PF administration significantly improved defecation patterns, defecation retention, and colon transit time.
PF could be an effective aid to improve colonic motility and constipation.
American Psychological Association (APA)
Kim, Ji Hee& Lee, Su Kyung& Joo, Min Cheol. 2016. Effects and Safety of Aqueous Extract of Poncirus fructus in Spinal Cord Injury with Neurogenic Bowel. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104323
Modern Language Association (MLA)
Kim, Ji Hee…[et al.]. Effects and Safety of Aqueous Extract of Poncirus fructus in Spinal Cord Injury with Neurogenic Bowel. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1104323
American Medical Association (AMA)
Kim, Ji Hee& Lee, Su Kyung& Joo, Min Cheol. Effects and Safety of Aqueous Extract of Poncirus fructus in Spinal Cord Injury with Neurogenic Bowel. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104323
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104323