The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress
Joint Authors
Wu, Longhuo
Yang, Jianqiong
Liu, Hai
Shi, Weimei
Yuan, Xiaoliang
Li, Linfu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-03
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
ER stress has been implicated in pathophysiological development of many diseases.
Persistent overwhelming stimuli trigger ER stress to initiate apoptosis, autophagy, and cell death.
IRE1-JNK and eIF2α-CHOP signaling pathways are the two important players of ER stress, which is also modulated by ROS production, calcium disturbance, and inflammatory factors.
ER stress has been developed as a novel strategy for diseases management.
Recently, a vast of research focuses on the natural occurring compounds targeting ER stress, which results in medical benefits to human diseases.
These small reported molecules mainly include polyphenols, alkaloids, and saponins.
Many of them have been developed for use in clinical applications.
To better understand the pharmacological mechanism of these molecules in ER stress in diseases, efforts have been made to discover and deliver medical merits.
In this paper, we will summarize the natural occurring compounds targeting ER stress.
American Psychological Association (APA)
Liu, Hai& Yang, Jianqiong& Li, Linfu& Shi, Weimei& Yuan, Xiaoliang& Wu, Longhuo. 2016. The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1104376
Modern Language Association (MLA)
Liu, Hai…[et al.]. The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1104376
American Medical Association (AMA)
Liu, Hai& Yang, Jianqiong& Li, Linfu& Shi, Weimei& Yuan, Xiaoliang& Wu, Longhuo. The Natural Occurring Compounds Targeting Endoplasmic Reticulum Stress. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1104376
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104376