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Evaluation of Wound Healing Properties of Grape Seed, Sesame, and Fenugreek Oils
Joint Authors
Ben Khedir, Sameh
Moalla, Dorsaf
Sahnoun, Zouheir
Ksouda Moalla, Kamilia
Kammoun, Naziha Grati
Rebai, Tarek
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-20
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Background.
Medicinal plants have proved at all times to be a powerful remedy for health care.
Accordingly, grape seed, sesame, and fenugreek extracted oils with pharmacological properties are investigated as wound treatments.
This study assesses the potential of our oils for healing wounds induced on rats.
Methods.
Phytochemical analyses of oils have involved: quality value, polyphenol, chlorophylls, carotene, and fatty acids.
Antibacterial activity was carried out.
Antioxidant activity was evaluated: the scavenging effect on DPPH radicals, the reducing power, and β-carotene discoloration.
Uniform wound excision was induced on rats dorsum randomly divided into five groups: groups treated with “CICAFLORA®” and tested oils and untreated one.
The posthealing biopsies were histologically assessed.
Results.
Wound biopsies treated with oils showed the best tissue regeneration compared to control groups.
Groups treated with our oils and “CICAFLORA” had higher wound contraction percentage.
Polyunsaturated fatty acids in oils act as inflammatory mediators increasing neovascularization, extracellular remodeling, migration, and cell differentiation.
Wound healing effect was attributed to antibacterial and antioxidant synergy.
Conclusion.
According to findings, oils showed better activity in wound healing compared to “CICAFLORA” due to a phytoconstituents synergy.
However, clinical trials on humans are necessary to confirm efficacy on human pathology.
American Psychological Association (APA)
Moalla, Dorsaf& Ben Khedir, Sameh& Ksouda Moalla, Kamilia& Kammoun, Naziha Grati& Rebai, Tarek& Sahnoun, Zouheir. 2016. Evaluation of Wound Healing Properties of Grape Seed, Sesame, and Fenugreek Oils. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104396
Modern Language Association (MLA)
Moalla, Dorsaf…[et al.]. Evaluation of Wound Healing Properties of Grape Seed, Sesame, and Fenugreek Oils. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1104396
American Medical Association (AMA)
Moalla, Dorsaf& Ben Khedir, Sameh& Ksouda Moalla, Kamilia& Kammoun, Naziha Grati& Rebai, Tarek& Sahnoun, Zouheir. Evaluation of Wound Healing Properties of Grape Seed, Sesame, and Fenugreek Oils. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1104396
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104396