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Composition Analysis and Inhibitory Effect of Sterculia lychnophora against Biofilm Formation by Streptococcus mutans
Joint Authors
You, Yong-Ouk
Yang, Yang
Hwang, Eun-Hee
Park, Bok-Im
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Pangdahai is a traditional Chinese drug, specifically described in the Chinese Pharmacopoeia as the seeds of Sterculia lychnophora Hance.
Here, we separated S.
lychnophora husk and kernel, analyzed the nutrient contents, and investigated the inhibitory effects of S.
lychnophora ethanol extracts on cariogenic properties of Streptococcus mutans, important bacteria in dental caries and plaque formation.
Ethanol extracts of S.
lychnophora showed dose-dependent antibacterial activity against S.
mutans with significant inhibition at concentrations higher than 0.01 mg/mL compared with the control group (p<0.05).
Furthermore, biofilm formation was decreased by S.
lychnophora at concentrations > 0.03 mg/mL, while bacterial viability was decreased dose-dependently at high concentrations (0.04, 0.08, 0.16, and 0.32 mg/mL).
Preliminary phytochemical analysis of the ethanol extract revealed a strong presence of alkaloid, phenolics, glycosides, and peptides while the presence of steroids, terpenoids, flavonoids, and organic acids was low.
The S.
lychnophora husk had higher moisture and ash content than the kernel, while the protein and fat content of the husk were lower (p<0.05) than those of the kernel.
These results indicate that S.
lychnophora may have antibacterial effects against S.
mutans, which are likely related to the alkaloid, phenolics, glycosides, and peptides, the major components of S.
lychnophora.
American Psychological Association (APA)
Yang, Yang& Park, Bok-Im& Hwang, Eun-Hee& You, Yong-Ouk. 2016. Composition Analysis and Inhibitory Effect of Sterculia lychnophora against Biofilm Formation by Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104408
Modern Language Association (MLA)
Yang, Yang…[et al.]. Composition Analysis and Inhibitory Effect of Sterculia lychnophora against Biofilm Formation by Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104408
American Medical Association (AMA)
Yang, Yang& Park, Bok-Im& Hwang, Eun-Hee& You, Yong-Ouk. Composition Analysis and Inhibitory Effect of Sterculia lychnophora against Biofilm Formation by Streptococcus mutans. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104408
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104408