Antidiabetic Properties, Bioactive Constituents, and Other Therapeutic Effects of Scoparia dulcis

Joint Authors

Waisundara, Viduranga Y.
Pamunuwa, Geethi
Karunaratne, D. Nedra

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-08-10

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Medicine

Abstract EN

This review discusses the antidiabetic activities of Scoparia dulcis as well as its antioxidant and anti-inflammatory properties in relation to the diabetes and its complications.

Ethnomedical applications of the herb have been identified as treatment for jaundice, stomach problems, skin disease, fever, and kidney stones, reproductory issues, and piles.

Evidence has been demonstrated through scientific studies as to the antidiabetic effects of crude extracts of S.

dulcis as well as its bioactive constituents.

The primary mechanisms of action of antidiabetic activity of the plant and its bioactive constituents are through α-glucosidase inhibition, curbing of PPAR-γ and increased secretion of insulin.

Scoparic acid A, scoparic acid D, scutellarein, apigenin, luteolin, coixol, and glutinol are some of the compounds which have been identified as responsible for these mechanisms of action.

S.

dulcis has also been shown to exhibit analgesic, antimalarial, hepatoprotective, sedative, hypnotic, antiulcer, antisickling, and antimicrobial activities.

Given this evidence, it may be concluded that S.

dulcis could be promoted among the masses as an alternative and complementary therapy for diabetes, provided further scientific studies on the toxicological and pharmacological aspects are carried out through either in vivo or clinical means.

American Psychological Association (APA)

Pamunuwa, Geethi& Karunaratne, D. Nedra& Waisundara, Viduranga Y.. 2016. Antidiabetic Properties, Bioactive Constituents, and Other Therapeutic Effects of Scoparia dulcis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104414

Modern Language Association (MLA)

Pamunuwa, Geethi…[et al.]. Antidiabetic Properties, Bioactive Constituents, and Other Therapeutic Effects of Scoparia dulcis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1104414

American Medical Association (AMA)

Pamunuwa, Geethi& Karunaratne, D. Nedra& Waisundara, Viduranga Y.. Antidiabetic Properties, Bioactive Constituents, and Other Therapeutic Effects of Scoparia dulcis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1104414

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1104414