Effects of Transcutaneous Electrical Acustimulation on Refractory Gastroesophageal Reflux Disease
Joint Authors
Chen, Jiande DZ
Jin, Hai-feng
LU, Bin
Meng, Li-na
Chen, Shanshan
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-28
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To investigate effects and possible mechanisms of transcutaneous electrical acustimulation (TEA) performed by a wearable watch-size stimulator for refractory gastroesophageal reflux disease (RGERD).
Methods.
Twenty patients diagnosed as RGERD were enrolled in the study and randomly divided into four groups: esomeprazole group (Group A), esomeprazole combined with TEA group (Group B), esomeprazole combined with sham-TEA group (Group C), and esomeprazole combined with domperidone group (Group D).
HRM and 24 h pH-impedance monitoring and GerdQ score were used to measure related indexes before and after treatment.
Results.
(1) TEA significantly increased LESP, compared with PPI treatment only or PPI plus sham-TEA.
After pairwise comparison, LESP of Group B was increased more than Group A ( P = 0.008 ) or Group C ( P = 0.021 ).
(2) PPI plus TEA decreased not only the number of acid reflux episodes but also the number of weak acid reflux episodes ( P = 0.005 ).
(3) Heartburn and reflux symptoms were improved more with PPI + TEA than with PPI treatment only or PPI plus sham-TEA (GerdQ scores, P = 0.001 ).
Conclusion.
TEA can improve symptoms in RGERD patients by increasing LESP and decreasing events of weak acid reflux and acid reflux; addition of TEA to esomeprazole significantly enhances the effect of TEA.
American Psychological Association (APA)
Meng, Li-na& Chen, Shanshan& Chen, Jiande DZ& Jin, Hai-feng& LU, Bin. 2016. Effects of Transcutaneous Electrical Acustimulation on Refractory Gastroesophageal Reflux Disease. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104415
Modern Language Association (MLA)
Meng, Li-na…[et al.]. Effects of Transcutaneous Electrical Acustimulation on Refractory Gastroesophageal Reflux Disease. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1104415
American Medical Association (AMA)
Meng, Li-na& Chen, Shanshan& Chen, Jiande DZ& Jin, Hai-feng& LU, Bin. Effects of Transcutaneous Electrical Acustimulation on Refractory Gastroesophageal Reflux Disease. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1104415
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104415