An Overview of Systematic Reviews of Danhong Injection for Ischemic Stroke
Joint Authors
Wang, Hui
Ren, Shutian
Liu, Chunxiang
Zhang, Xiaoxia
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
This overview is to evaluate the current evidence from systematic reviews (SRs) of Danhong injection (DHI) for ischemic stroke (IS).
Methods.
SRs of randomized controlled trials (RCTs) concerning DHI and IS were searched in six databases without language restrictions until September 2015.
Assessment of multiple systematic reviews (AMSTAR) was used to evaluate the methodological quality of all included SRs.
Result.
A total of 8 articles were included.
After the administration of DHI, clinical efficiency and neurological deficits score have marked advantages over those of the control group.
However, the overall poor quality of meta-analysis and original studies affected the reliability of the results.
Evaluation of methodological quality found that no one paper meets the requirements of all 11 items.
The main flaws of the methodology quality included the following: not providing “a priori” design and reasonable objectives, duplicate study selection not given enough attention, performing an incomprehensive literature search, not paying attention to publication bias and other bias reports, characteristics of included studies not provided in detail, and ignoring clinical heterogeneity when performing meta-analyses.
Conclusion.
The current published SRs suggest DHI appears to be a safe and effective way for IS treatment in general.
However, it lacks a high quality systematic evaluation and analysis.
The quality of SRs should be improved.
Further large sample-size and well-designed RCTs are needed.
American Psychological Association (APA)
Wang, Hui& Ren, Shutian& Liu, Chunxiang& Zhang, Xiaoxia. 2016. An Overview of Systematic Reviews of Danhong Injection for Ischemic Stroke. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104457
Modern Language Association (MLA)
Wang, Hui…[et al.]. An Overview of Systematic Reviews of Danhong Injection for Ischemic Stroke. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1104457
American Medical Association (AMA)
Wang, Hui& Ren, Shutian& Liu, Chunxiang& Zhang, Xiaoxia. An Overview of Systematic Reviews of Danhong Injection for Ischemic Stroke. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104457
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104457