Chinese Herbal Medicine as an Adjunctive Therapy for Breast Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Zhu, Li Bing
Li, Yingshuai
Wang, Qi
Li, Lingru
Wang, Ji
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-09
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Chinese herbal medicine (CHM) has been widely used as an adjunctive therapy for breast cancer, while its efficacy remains unexplored.
The purpose of this study is to evaluate the efficacy of CHM combined with chemotherapy for breast cancer.
The study results showed that CHM combined with chemotherapy significantly increased tumor response and KPS as compared to using chemotherapy alone (RR = 1.36; 95% CI = 1.24–1.48; P < 0.00001 ; RR = 1.38; 95% CI = 1.26–1.52; P < 0.00001 , resp.).
Besides, CHM as an adjunctive therapy significantly reduced the nausea and vomiting at toxicity grade of III–IV (RR = 0.37; 95% CI = 0.27–0.52; P < 0.00001 ).
Moreover, the combined therapy significantly prevented the decline of WBC in patients under chemotherapy at toxicity grade of III–IV (RR = 0.49; 95% CI = 0.34–0.69; P < 0.00001 ) and prevented the decline of platelet at toxicity grade of III–IV or I–IV (RR = 0.29; 95% CI = 0.12–0.73; P = 0.008 ; RR = 0.77; 95% CI = 0.63–0.94; P = 0.009 , resp.).
This study suggests that CHM combined with chemotherapy in comparison with chemotherapy alone can significantly enhance tumor response, improve KPS, and alleviate toxicity induced by chemotherapy in breast cancer patients.
However, a firm conclusion could not be reached due to the lack of high quality trials and large-scale RCTs, so further trials with higher quality and larger scale are needed.
American Psychological Association (APA)
Zhu, Li Bing& Li, Lingru& Li, Yingshuai& Wang, Ji& Wang, Qi. 2016. Chinese Herbal Medicine as an Adjunctive Therapy for Breast Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1104507
Modern Language Association (MLA)
Zhu, Li Bing…[et al.]. Chinese Herbal Medicine as an Adjunctive Therapy for Breast Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-17.
https://search.emarefa.net/detail/BIM-1104507
American Medical Association (AMA)
Zhu, Li Bing& Li, Lingru& Li, Yingshuai& Wang, Ji& Wang, Qi. Chinese Herbal Medicine as an Adjunctive Therapy for Breast Cancer: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1104507
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104507