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The Efficacy and Safety of Jaungo, a Traditional Medicinal Ointment, in Preventing Radiation Dermatitis in Patients with Breast Cancer: A Prospective, Single-Blinded, Randomized Pilot Study
Joint Authors
Hwang, Deok-Sang
Kong, Moonkyoo
Lee, Jee Young
Yoon, Seong Woo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
This study was performed to evaluate the efficacy and safety of Jaungo in preventing radiation dermatitis in patients with breast cancer.
Methods.
Thirty patients were prospectively enrolled and randomly assigned to receive Jaungo or general supportive skin care.
Radiation dermatitis and pain were examined at daily intervals from the start of radiotherapy until 4 weeks after its completion.
The primary endpoint of this study was the incidence of radiation dermatitis.
The secondary endpoints were time to onset of radiation dermatitis, duration of radiation dermatitis, and maximum pain score.
Results.
Jaungo reduced the incidence of grade ≥2 (46.7% versus 78.6%) and grade 3 radiation dermatitis (20.0% versus 50.0%) in comparison with general supportive skin care.
Jaungo also delayed the onset of grade 2 dermatitis (35 days versus 30 days).
In terms of time to onset of grade 3 dermatitis, duration of dermatitis, and maximum pain score, Jaungo showed results comparable to those achieved with general supportive skin care.
No patients experienced adverse effects caused by Jaungo administration.
Conclusions.
Jaungo minimized radiation dermatitis in patients with breast cancer without causing adverse effects.
Further randomized studies with a larger sample size are required to assess clinical use of Jaungo.
American Psychological Association (APA)
Kong, Moonkyoo& Hwang, Deok-Sang& Lee, Jee Young& Yoon, Seong Woo. 2016. The Efficacy and Safety of Jaungo, a Traditional Medicinal Ointment, in Preventing Radiation Dermatitis in Patients with Breast Cancer: A Prospective, Single-Blinded, Randomized Pilot Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104509
Modern Language Association (MLA)
Kong, Moonkyoo…[et al.]. The Efficacy and Safety of Jaungo, a Traditional Medicinal Ointment, in Preventing Radiation Dermatitis in Patients with Breast Cancer: A Prospective, Single-Blinded, Randomized Pilot Study. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1104509
American Medical Association (AMA)
Kong, Moonkyoo& Hwang, Deok-Sang& Lee, Jee Young& Yoon, Seong Woo. The Efficacy and Safety of Jaungo, a Traditional Medicinal Ointment, in Preventing Radiation Dermatitis in Patients with Breast Cancer: A Prospective, Single-Blinded, Randomized Pilot Study. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104509
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104509