Rice Germosprout Extract Protects Erythrocytes from Hemolysis and the Aorta, Brain, Heart, and Liver Tissues from Oxidative Stress In Vitro
Joint Authors
Shahdat, Hossain Md
Bhowmick, Sujan
Islam, Saiful
Hassan, Mehedi
Sarkar, Marzan
Shahjalal, Hussain
Hussain, Jakir
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Identifying dietary alternatives for artificial antioxidants capable of boosting antihemolytic and antioxidative defense has been an important endeavor in improving human health.
In the present study, we studied antihemolytic and antioxidative effects of germosprout (i.e., the germ part along with sprouted stems plus roots) extract prepared from the pregerminated rice.
The extract contained considerable amounts of antioxidant β -carotene ( 414 ± 12 ng/g of extract) and phytochemicals such as total polyphenols ( 12.0 ± 1.1 mg gallic acid equivalent/g of extract) and flavonoids ( 11.0 ± 1.4 mg catechin equivalent/g of extract).
The antioxidant potential of the extract was assessed by its DPPH- (2,2-diphenyl-1-picrylhydrazyl-) free radical scavenging activity where we observed that germosprout extract had considerable antioxidative potentials.
To evaluate antihemolytic effect of the extract, freshly prepared erythrocytes were incubated with either peroxynitrite or Fenton’s reagent in the absence or presence of the extract.
We observed that erythrocytes pretreated with the extract exhibited reduced degree of in vitro hemolysis.
To support the proposition that germosprout extract could act as a good antioxidative agent, we also induced in vitro oxidative stress in erythrocyte membranes and in the aorta, brain, heart, and liver tissue homogenates in the presence of the extract.
As expected, germosprout extract decreased oxidative stress almost to the same extent as that of vitamin E, as measured by lipid peroxide levels, in all the mentioned tissues.
We conclude that rice germosprout extract could be a good natural source of antioxidants to reduce oxidative stress-induced hemolysis and damage of blood vessels and other tissues.
American Psychological Association (APA)
Shahdat, Hossain Md& Bhowmick, Sujan& Sarkar, Marzan& Hassan, Mehedi& Hussain, Jakir& Islam, Saiful…[et al.]. 2016. Rice Germosprout Extract Protects Erythrocytes from Hemolysis and the Aorta, Brain, Heart, and Liver Tissues from Oxidative Stress In Vitro. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104516
Modern Language Association (MLA)
Shahdat, Hossain Md…[et al.]. Rice Germosprout Extract Protects Erythrocytes from Hemolysis and the Aorta, Brain, Heart, and Liver Tissues from Oxidative Stress In Vitro. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104516
American Medical Association (AMA)
Shahdat, Hossain Md& Bhowmick, Sujan& Sarkar, Marzan& Hassan, Mehedi& Hussain, Jakir& Islam, Saiful…[et al.]. Rice Germosprout Extract Protects Erythrocytes from Hemolysis and the Aorta, Brain, Heart, and Liver Tissues from Oxidative Stress In Vitro. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104516
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104516