Anticancer Activity, Antioxidant Activity, and Phenolic and Flavonoids Content of Wild Tragopogon porrifolius Plant Extracts
Joint Authors
Rishmawi, Suzi
Ariqat, Sharehan H.
Khalid, Mahmoud F.
Warad, Ismail
Salah, Zaidoun
al-Rimawi, Fuad
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Tragopogon porrifolius, commonly referred to as white salsify, is an edible herb used in folk medicine to treat cancer.
Samples of Tragopogon porrifolius plant grown wild in Palestine were extracted with different solvents: water, 80% ethanol, and 100% ethanol.
The extracts were analyzed for their total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (AA).
Four different antioxidant assays were used to evaluate AA of the extracts: two measures the reducing power of the extracts (ferric reducing antioxidant power (FRAP) and cupric reducing antioxidant power (CUPRAC)), while two other assays measure the scavenging ability of the extracts (2,2-azino-di-(3-ethylbenzothialozine-sulphonic acid (ABTS)) and 2,2-diphenyl-1-picrylhydrazyl (DPPH)).
Anticancer activity of the plant extracts were also tested on HOS and KHOS osteosarcoma cell lines.
The results revealed that the polarity of the extraction solvent affects the TPC, TFC, and AA.
It was found that both TPC and AA are highest for plant extracted with 80% ethanol, followed by water, and finally with 100% ethanol.
TFC however was the highest in the following order: 80% ethanol > 100% ethanol > water.
The plant extracts showed anticancer activities against KHOS cancer cell lines; they reduced total cell count and induced cell death in a drastic manner.
American Psychological Association (APA)
al-Rimawi, Fuad& Rishmawi, Suzi& Ariqat, Sharehan H.& Khalid, Mahmoud F.& Warad, Ismail& Salah, Zaidoun. 2016. Anticancer Activity, Antioxidant Activity, and Phenolic and Flavonoids Content of Wild Tragopogon porrifolius Plant Extracts. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104519
Modern Language Association (MLA)
al-Rimawi, Fuad…[et al.]. Anticancer Activity, Antioxidant Activity, and Phenolic and Flavonoids Content of Wild Tragopogon porrifolius Plant Extracts. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1104519
American Medical Association (AMA)
al-Rimawi, Fuad& Rishmawi, Suzi& Ariqat, Sharehan H.& Khalid, Mahmoud F.& Warad, Ismail& Salah, Zaidoun. Anticancer Activity, Antioxidant Activity, and Phenolic and Flavonoids Content of Wild Tragopogon porrifolius Plant Extracts. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1104519
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104519