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Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease
Joint Authors
Liu, Boyan
Du, Yanhui
Cong, Lixin
Jia, Xiaoying
Yang, Ge
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Danshen was able to reduce the risk of the patients with coronary heart disease (CHD), but the mechanism is still widely unknown.
Biochemical indices (lipid profile, markers of renal and liver function, and homocysteine (Hcy)) are closely associated with CHD risk.
We aimed to investigate whether the medicine reduces CHD risk by improving these biochemical indices.
The patients received 10 Danshen pills (27 mg/pill) in Dashen group, while the control patients received placebo pills, three times daily.
The duration of follow-up was three months.
The serum biochemical indices were measured, including lipid profiles (LDL cholesterol (LDL-C), HDL-C, total cholesterol (TC), triglycerides (TG), apolipoprotein (Apo) A, ApoB, ApoE, and lipoprotein (a) (Lp(a))); markers of liver function (gamma-glutamyl transpeptidase (GGT), total bilirubin (TBil), indirect bilirubin (IBil), and direct bilirubin (DBil)); marker of renal function (uric acid (UA)) and Hcy.
After three-month follow-up, Danshen treatment reduced the levels of TG, TC, LDL-C, Lp(a), GGT, DBil, UA, and Hcy ( P < 0.05 ).
In contrast, the treatment increased the levels of HDL-C, ApoA, ApoB, ApoE, TBil, and IBil ( P < 0.05 ).
Conclusion.
Danshen can reduce the CHD risk by improving the biochemical indices of CHD patients.
American Psychological Association (APA)
Liu, Boyan& Du, Yanhui& Cong, Lixin& Jia, Xiaoying& Yang, Ge. 2016. Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease. Evidence-Based Complementary and Alternative Medicine،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104534
Modern Language Association (MLA)
Liu, Boyan…[et al.]. Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease. Evidence-Based Complementary and Alternative Medicine No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1104534
American Medical Association (AMA)
Liu, Boyan& Du, Yanhui& Cong, Lixin& Jia, Xiaoying& Yang, Ge. Danshen (Salvia miltiorrhiza) Compounds Improve the Biochemical Indices of the Patients with Coronary Heart Disease. Evidence-Based Complementary and Alternative Medicine. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1104534
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1104534